C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: X-ray repair complementing defective repair in Chinese hamster cells 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022471 Xrcc6 10090 + 15:81987835-82040085 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069530 Xrcc6-001 82016369-82040085 protein_coding
  ENSMUST00000100399 Xrcc6-002 82015519-82040085 protein_coding
  ENSMUST00000164775 Xrcc6-008 82029060-82037491 retained_intron
  ENSMUST00000164779 Xrcc6-005 82016515-82025686 protein_coding
  ENSMUST00000164920 Xrcc6-011 82028064-82039802 processed_transcript
  ENSMUST00000164975 Xrcc6-007 82022283-82022930 retained_intron
  ENSMUST00000165777 Xrcc6-004 81987835-82022574 protein_coding
  ENSMUST00000166311 Xrcc6-010 82025389-82029592 retained_intron
  ENSMUST00000168581 Xrcc6-006 82016461-82023034 protein_coding
  ENSMUST00000170630 Xrcc6-012 82016464-82025637 protein_coding
  ENSMUST00000170907 Xrcc6-009 82022976-82027756 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000069530ENSMUST00000164920ENSMUST00000166311
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000069530 7.740±0.50 6.657±0.71 5.569±0.26 7.574±0.37 3.760±0.32 4.393±0.37 4.866±0.31 11.732±7.00 3.462±0.00 8.596±0.94 8.505±4.90 8.565±5.05
ENSMUST00000164920 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 40.869±0.00 91.937±0.00
ENSMUST00000166311 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 28.194±0.00 41.171±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000723 IEA telomere maintenance
GO:0003684 IEA damaged DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003691 IEA double-stranded telomeric DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005694 IEA chromosome
GO:0005730 IEA nucleolus
GO:0005737 IDA cytoplasm
GO:0006302 IMP double-strand break repair
GO:0006303 IMP:ISS double-strand break repair via nonhomologous end joining
GO:0006351 IEA transcription, DNA-templated
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007420 IEA brain development
GO:0008022 IEA protein C-terminus binding
GO:0010212 IMP response to ionizing radiation
GO:0016020 IEA membrane
GO:0032508 IEA DNA duplex unwinding
GO:0033151 IMP V(D)J recombination
GO:0042162 IEA telomeric DNA binding
GO:0043234 IEA protein complex
GO:0043564 IEA:ISS Ku70:Ku80 complex
GO:0044212 IEA transcription regulatory region DNA binding
GO:0044822 IEA poly(A) RNA binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050769 IMP positive regulation of neurogenesis
GO:0051575 ISS 5'-deoxyribose-5-phosphate lyase activity
GO:0070419 ISS nonhomologous end joining complex
GO:0071475 IEA cellular hyperosmotic salinity response
GO:0071481 IEA cellular response to X-ray

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000071551 xrcc6 X-ray repair complementing defective repair in Chinese hamster cells 6 protein_coding Danio_rerio
ENSDARG00000090718 OTTDARG00000020547 Uncharacterized protein protein_coding Danio_rerio
ENSG00000196419 XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 protein_coding Homo_sapiens

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