C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) peptidase inhibitor, clade D, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022766 Serpind1 10090 + 16:17331371-17343575 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023450 Serpind1-001 17331371-17343575 protein_coding
  ENSMUST00000161034 Serpind1-002 17331383-17343574 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023450ENSMUST00000161034
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023450 0.157±0.01 0.047±0.00 0.088±0.00 0.040±0.00 0.687±0.10 N/A 0.111±0.02 0.316±0.00 117.592±50.52 0.652±0.29 N/A 0.143±0.00 14.925±10.39 0.038±0.01
ENSMUST00000161034 0.258±0.13 0.238±0.04 0.051±0.01 0.391±0.12 0.299±0.06 0.145±0.05 0.189±0.10 0.378±0.03 88.943±19.09 0.589±0.12 0.075±0.03 0.200±0.13 13.220±15.32 0.080±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008PT CIL_0008PT_0002 VISTA 16:16870677-17470725
CIL_0003KR CIL_0003KR_0003 CGP 16:17280351-17406314
CIL_0003KQ CIL_0003KQ_0003 CGP 16:17331371-17430826

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005615 IEA extracellular space
GO:0007596 IEA blood coagulation
GO:0008201 IEA heparin binding
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021208 serpind1 serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 protein_coding Danio_rerio
ENSG00000099937 SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 protein_coding Homo_sapiens

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