Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSG00000099937	SERPIND1	9606	+	22:20773879-20787720	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENST00000215727		SERPIND1-001	20773879-20787720	protein_coding
	ENST00000406799		SERPIND1-002	20779181-20787232	protein_coding

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENST00000215727	0.099±0.00	0.176±0.00	N/A	0.409±0.00	0.018±0.00	N/A	0.058±0.02	117.858±117.81	103.270±0.00	1.083±0.00	N/A	0.530±0.32	0.715±0.72	0.246±0.19
ENST00000406799	N/A	N/A	0.055±0.00	0.985±0.00	0.267±0.11	0.026±0.00	0.059±0.02	N/A	N/A	N/A	0.025±0.00	0.077±0.00	0.098±0.00	N/A

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0003KR	CIL_0003KR_0002	CGP	22:20707691-20859417
CIL_0003KQ	CIL_0003KQ_0002	CGP	22:20773879-20891218

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0004866	TAS	endopeptidase inhibitor activity
GO:0004867	IBA	serine-type endopeptidase inhibitor activity
GO:0005576	NAS	extracellular region
GO:0005615	IEA	extracellular space
GO:0006935	IEA	chemotaxis
GO:0007596	IEA	blood coagulation
GO:0008201	IEA	heparin binding
GO:0010951	IBA	negative regulation of endopeptidase activity
GO:0030162	IBA	regulation of proteolysis
GO:0070062	IDA	extracellular vesicular exosome

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000021208	serpind1	serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1	protein_coding	Danio_rerio
ENSMUSG00000022766	Serpind1	serine (or cysteine) peptidase inhibitor, clade D, member 1	protein_coding	Mus_musculus

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