C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: FYVE, RhoGEF and PH domain containing 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022788 Fgd4 10090 - 16:16416917-16600549 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069284 Fgd4-006 16422602-16527411 protein_coding
  ENSMUST00000159058 Fgd4-005 16472266-16559990 retained_intron
  ENSMUST00000159542 Fgd4-010 16462014-16600549 protein_coding
  ENSMUST00000161188 Fgd4-201 16435706-16504222 protein_coding
  ENSMUST00000161624 Fgd4-009 16487115-16600345 retained_intron
  ENSMUST00000161861 Fgd4-001 16416917-16560219 protein_coding
  ENSMUST00000162045 Fgd4-003 16452719-16560211 protein_coding
  ENSMUST00000162124 Fgd4-004 16453480-16560211 protein_coding
  ENSMUST00000162414 Fgd4-007 16482492-16600039 retained_intron
  ENSMUST00000162542 Fgd4-011 16483471-16527411 retained_intron
  ENSMUST00000162671 Fgd4-008 16422563-16599978 protein_coding
  ENSMUST00000172181 Fgd4-002 16435706-16560046 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000069284ENSMUST00000161624ENSMUST00000161861ENSMUST00000162414ENSMUST00000162671
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000069284 0.768±0.00 N/A N/A 0.838±0.30 N/A 1.664±0.35 2.188±0.78 0.392±0.00 N/A N/A N/A N/A
ENSMUST00000161624 0.904±0.00 N/A 7.767±3.12 1.388±0.59 N/A 0.793±0.06 1.239±0.15 0.835±0.37 1.351±0.00 2.248±1.51 1.475±0.24 4.071±3.01
ENSMUST00000161861 N/A 0.489±0.00 6.104±0.01 0.463±0.09 1.247±0.33 N/A N/A 0.164±0.04 N/A 1.177±0.30 0.681±0.00 0.311±0.05
ENSMUST00000162414 N/A 0.737±0.11 N/A N/A 3.649±1.26 N/A N/A N/A N/A 2.503±0.52 N/A N/A
ENSMUST00000162671 0.932±0.30 1.166±0.34 N/A 0.721±0.00 2.573±0.71 N/A N/A 0.881±0.15 1.091±0.02 2.396±0.89 4.800±1.80 0.489±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 ISO actin binding
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0007257 ISO activation of JUN kinase activity
GO:0015629 IEA actin cytoskeleton
GO:0030027 IDA lamellipodium
GO:0030032 IDA lamellipodium assembly
GO:0030035 IDA microspike assembly
GO:0030175 IDA filopodium
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011830 fgd4a FYVE, RhoGEF and PH domain containing 4a protein_coding Danio_rerio
ENSDARG00000060248 CABZ01078314.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000139132 FGD4 FYVE, RhoGEF and PH domain containing 4 protein_coding Homo_sapiens

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