C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FYVE, RhoGEF and PH domain containing 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000161861 Fgd4-001 ENSMUSG00000022788 10090 - 16:16416917-16560219 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonLiverOvaryPlacentaTestisENSMUST00000161861
Transcript ID Adrenal Brain Breast Colon Liver Ovary Placenta Testis
ENSMUST00000161861 0.489±0.00 6.104±0.01 0.463±0.09 1.247±0.33 0.164±0.04 1.177±0.30 0.681±0.00 0.311±0.05

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003779 ISO actin binding
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0007257 ISO activation of JUN kinase activity
GO:0015629 IEA actin cytoskeleton
GO:0030027 IDA lamellipodium
GO:0030032 IDA lamellipodium assembly
GO:0030035 IDA microspike assembly
GO:0030175 IDA filopodium
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000395740 FGD4-003 nonsense_mediated_decay Homo_sapiens 0 1757
ENST00000427716 FGD4-001 protein_coding Homo_sapiens 0 2856
ENST00000472289 FGD4-005 protein_coding Homo_sapiens 0 464
ENST00000473513 FGD4-008 processed_transcript Homo_sapiens 0 261
ENST00000493087 FGD4-002 nonsense_mediated_decay Homo_sapiens 0 1969
ENST00000494977 FGD4-004 nonsense_mediated_decay Homo_sapiens 0 1146
ENST00000525053 FGD4-011 protein_coding Homo_sapiens 0 2667
ENST00000531134 FGD4-010 protein_coding Homo_sapiens 0 2671
ENST00000534526 FGD4-013 protein_coding Homo_sapiens 0 2608
ENST00000546442 FGD4-015 protein_coding Homo_sapiens 0 2610
ENST00000551984 FGD4-014 nonsense_mediated_decay Homo_sapiens 0 2218
ENST00000583694 FGD4-017 protein_coding Homo_sapiens 0 259

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