C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane BAX inhibitor motif containing 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023010 Tmbim6 10090 + 15:99392882-99410049 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023749 Tmbim6-001 99392882-99410049 protein_coding
  ENSMUST00000159209 Tmbim6-006 99393219-99408535 protein_coding
  ENSMUST00000159531 Tmbim6-002 99393610-99408610 protein_coding
  ENSMUST00000160454 Tmbim6-009 99405874-99408791 retained_intron
  ENSMUST00000160635 Tmbim6-004 99392986-99408536 protein_coding
  ENSMUST00000161250 Tmbim6-003 99392986-99408634 protein_coding
  ENSMUST00000161778 Tmbim6-007 99393022-99408491 protein_coding
  ENSMUST00000162274 Tmbim6-008 99401085-99402102 protein_coding
  ENSMUST00000162624 Tmbim6-005 99393592-99406677 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023749ENSMUST00000159209ENSMUST00000160635ENSMUST00000161778ENSMUST00000162624
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023749 179.197±31.56 243.952±17.49 148.542±12.93 57.022±8.64 168.339±63.79 252.725±53.58 52.050±7.06 702.251±34.28 285.895±186.05 337.536±2.29 69.848±7.15 117.026±62.32 115.636±31.96 38.410±13.48
ENSMUST00000159209 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 55.114±6.37
ENSMUST00000160635 N/A N/A N/A N/A 106.695±17.26 N/A 45.764±2.36 N/A N/A N/A N/A N/A 109.899±37.15 N/A
ENSMUST00000161778 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 95.904±0.00 N/A N/A
ENSMUST00000162624 79.161±0.00 269.708±30.40 N/A N/A 174.765±26.79 231.139±43.25 40.586±0.00 351.798±35.71 285.771±7.08 199.345±12.86 N/A 106.144±10.52 N/A 180.183±37.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009O CIL_00009O_0002 CGP 15:99317225-99410049
CIL_00003M CIL_00003M_0002 CGP 15:99392882-99457748

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005783 IEA endoplasmic reticulum
GO:0006986 IEA response to unfolded protein
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0032469 IDA endoplasmic reticulum calcium ion homeostasis
GO:0043066 IEA negative regulation of apoptotic process
GO:0070059 IDA intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1902236 IGI negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077934 tegt testis enhanced gene transcript (BAX inhibitor 1) protein_coding Danio_rerio
ENSG00000139644 TMBIM6 transmembrane BAX inhibitor motif containing 6 protein_coding Homo_sapiens

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