C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, metabotropic 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023192 Grm2 10090 - 9:106643095-106656082 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023959 Grm2-002 106643117-106656080 protein_coding
  ENSMUST00000188527 Grm2-003 106643095-106648103 protein_coding
  ENSMUST00000189020 Grm2-001 106644885-106656082 protein_coding
  ENSMUST00000191330 Grm2-004 106644984-106646613 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023959ENSMUST00000188527ENSMUST00000189020ENSMUST00000191330
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023959 N/A N/A 2.279±0.30 0.018±0.01 N/A N/A 0.009±0.00 0.012±0.01 0.006±0.00 0.014±0.00 0.287±0.15 0.003±0.00 0.063±0.00
ENSMUST00000188527 0.013±0.00 0.004±0.00 N/A 0.014±0.00 0.022±0.00 N/A N/A N/A N/A N/A 0.804±0.33 0.005±0.00 0.255±0.14
ENSMUST00000189020 N/A 0.004±0.00 3.416±3.26 N/A 0.031±0.01 0.028±0.00 N/A 0.004±0.00 N/A N/A 0.166±0.04 0.005±0.00 N/A
ENSMUST00000191330 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.034±1.22 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NT CIL_0008NT_0002 VISTA 9:106082995-106685663
CIL_00087C CIL_00087C_0002 VISTA 9:106116951-106718793

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001641 IDA group II metabotropic glutamate receptor activity
GO:0005246 IDA calcium channel regulator activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005887 IBA integral component of plasma membrane
GO:0007196 IDA adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0014047 IEA glutamate secretion
GO:0030054 IEA cell junction
GO:0030424 IEA axon
GO:0042734 IBA presynaptic membrane
GO:0043005 IDA neuron projection
GO:0051966 IBA regulation of synaptic transmission, glutamatergic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004150 grm2a glutamate receptor, metabotropic 2a protein_coding Danio_rerio
ENSDARG00000007195 GRM2 (2 of 2) glutamate receptor, metabotropic 2 protein_coding Danio_rerio
ENSG00000164082 GRM2 glutamate receptor, metabotropic 2 protein_coding Homo_sapiens

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