C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, metabotropic 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000023959 Grm2-002 ENSMUSG00000023192 10090 - 9:106643117-106656080 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023959
Transcript ID Brain Breast Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023959 2.279±0.30 0.018±0.01 0.009±0.00 0.012±0.01 0.006±0.00 0.014±0.00 0.287±0.15 0.003±0.00 0.063±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NT CIL_0008NT_0002 VISTA 9:106082995-106685663
CIL_00087C CIL_00087C_0002 VISTA 9:106116951-106718793

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001641 IDA group II metabotropic glutamate receptor activity
GO:0005246 IDA calcium channel regulator activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005887 IBA integral component of plasma membrane
GO:0007196 IDA adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0014047 IEA glutamate secretion
GO:0030054 IEA cell junction
GO:0030424 IEA axon
GO:0042734 IBA presynaptic membrane
GO:0043005 IDA neuron projection
GO:0051966 IBA regulation of synaptic transmission, glutamatergic

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000012940 GRM2 (2 of 2)-201 protein_coding Danio_rerio 0 355
ENST00000282753 GRM1-001 protein_coding Homo_sapiens 4e-24 119
ENST00000296479 GRM2-002 nonsense_mediated_decay Homo_sapiens 0 1786
ENST00000355289 GRM1-019 protein_coding Homo_sapiens 2e-24 119
ENST00000361719 GRM1-201 protein_coding Homo_sapiens 4e-24 119
ENST00000395052 GRM2-001 protein_coding Homo_sapiens 0 3675
ENST00000419928 GRM2-007 protein_coding Homo_sapiens 0 414
ENST00000442933 GRM2-005 protein_coding Homo_sapiens 0 1947
ENST00000464585 GRM2-004 retained_intron Homo_sapiens 0 2041
ENST00000475478 GRM2-003 processed_transcript Homo_sapiens 0 2041
ENST00000492807 GRM1-002 protein_coding Homo_sapiens 4e-24 119
ENST00000496661 GRM2-006 processed_transcript Homo_sapiens 0 1064
ENST00000507907 GRM1-020 protein_coding Homo_sapiens 2e-24 119

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