C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023353 Agap3 10090 + 5:24452177-24502047 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000024123 Agap3-201 24452177-24502047 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024123
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024123 9.002±2.63 13.329±3.14 14.092±3.42 24.282±11.05 11.676±5.87 10.169±1.38 5.290±2.51 6.170±2.92 4.293±1.91 19.105±3.05 2.328±0.94 19.647±8.33 13.111±6.54 3.325±1.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008T1 CIL_0008T1_0002 VISTA 5:24041638-24646055
CIL_0007RX CIL_0007RX_0002 VISTA 5:24430554-25031843
CIL_0003TG CIL_0003TG_0002 CGP 5:24445458-24502047
CIL_0004EO CIL_0004EO_0002 CGP 5:24452177-24527202

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000060 IMP protein import into nucleus, translocation
GO:0003924 IDA GTPase activity
GO:0005525 IEA GTP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006184 IEA GTP catabolic process
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0016020 IEA membrane
GO:0016605 ISO PML body
GO:0030578 ISO PML body organization
GO:0031593 IDA polyubiquitin binding
GO:0032312 IEA regulation of ARF GTPase activity
GO:0034614 IDA cellular response to reactive oxygen species
GO:0034644 ISO cellular response to UV
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0071944 IDA cell periphery

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087822 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 protein_coding Danio_rerio
ENSG00000133612 AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 protein_coding Homo_sapiens

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