C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133612 AGAP3 9606 + 7:151085831-151144436 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335367 AGAP3-005 151114678-151123638 protein_coding
  ENST00000397238 AGAP3-001 151086742-151144432 protein_coding
  ENST00000461065 AGAP3-007 151134425-151144436 protein_coding
  ENST00000463179 AGAP3-020 151120071-151121033 retained_intron
  ENST00000463381 AGAP3-002 151085867-151144434 protein_coding
  ENST00000467250 AGAP3-026 151134482-151136560 processed_transcript
  ENST00000467724 AGAP3-015 151117754-151122878 nonsense_mediated_decay
  ENST00000468796 AGAP3-016 151118209-151122793 protein_coding
  ENST00000469901 AGAP3-010 151087067-151118278 protein_coding
  ENST00000473140 AGAP3-013 151116307-151117682 retained_intron
  ENST00000473312 AGAP3-004 151086742-151123635 protein_coding
  ENST00000473633 AGAP3-008 151139568-151144432 retained_intron
  ENST00000475145 AGAP3-025 151120016-151123850 processed_transcript
  ENST00000476375 AGAP3-011 151089712-151118344 processed_transcript
  ENST00000478320 AGAP3-023 151128577-151138116 processed_transcript
  ENST00000479901 AGAP3-003 151086742-151123636 protein_coding
  ENST00000480106 AGAP3-017 151118268-151120143 processed_transcript
  ENST00000483971 AGAP3-024 151128596-151131286 processed_transcript
  ENST00000485904 AGAP3-021 151123622-151138286 processed_transcript
  ENST00000486946 AGAP3-019 151119197-151120733 processed_transcript
  ENST00000490097 AGAP3-009 151085831-151117776 processed_transcript
  ENST00000490839 AGAP3-014 151117392-151118162 retained_intron
  ENST00000492234 AGAP3-012 151112184-151118333 processed_transcript
  ENST00000494808 AGAP3-022 151128333-151134534 retained_intron
  ENST00000498559 AGAP3-018 151118294-151123876 retained_intron
  ENST00000622464 AGAP3-201 151086742-151144436 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397238ENST00000461065ENST00000463381ENST00000468796ENST00000469901ENST00000473312ENST00000473633ENST00000476375ENST00000479901ENST00000492234ENST00000622464
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397238 N/A 3.112±0.00 N/A 2.173±0.00 5.303±0.00 10.547±0.00 1.811±1.57 3.718±1.90 1.377±0.00 11.278±8.79 3.478±0.00 N/A 6.760±0.00 4.584±2.08
ENST00000461065 N/A 4.636±0.00 N/A N/A 6.706±0.00 9.216±0.00 N/A 2.776±0.00 3.302±0.00 19.404±0.00 1.602±0.00 13.342±0.00 2.877±0.00 6.177±0.00
ENST00000463381 N/A N/A N/A N/A N/A 5.167±0.00 N/A N/A 1.496±0.00 0.910±0.00 N/A 8.427±1.21 3.173±0.98 2.692±1.18
ENST00000468796 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.560±0.00 N/A N/A N/A
ENST00000469901 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 13.810±0.00 N/A N/A N/A
ENST00000473312 13.656±0.00 10.482±0.00 N/A 68.786±61.17 9.515±0.00 7.426±0.00 3.928±3.44 3.174±0.00 6.650±0.00 N/A 9.796±0.00 11.008±0.00 6.969±1.84 11.089±0.00
ENST00000473633 N/A N/A 0.544±0.00 N/A 0.884±0.00 0.767±0.00 0.135±0.00 N/A N/A N/A N/A N/A N/A 1.327±0.00
ENST00000476375 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.535±0.00 N/A N/A
ENST00000479901 N/A N/A N/A N/A N/A N/A 4.650±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000492234 N/A N/A N/A N/A N/A N/A N/A N/A 3.927±0.00 N/A 9.570±0.00 N/A N/A N/A
ENST00000622464 11.080±0.00 N/A 0.648±0.00 N/A 3.920±1.19 2.318±0.00 N/A 2.021±0.00 1.966±0.00 N/A N/A 15.278±11.08 8.147±1.61 2.251±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008T1 CIL_0008T1_0001 VISTA 7:150668461-151272977
CIL_0003TG CIL_0003TG_0001 CGP 7:151081080-151144436
CIL_0004EO CIL_0004EO_0001 CGP 7:151085831-151174745

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000060 IEA protein import into nucleus, translocation
GO:0003924 IEA GTPase activity
GO:0005515 IEA protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006184 IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0031593 IEA polyubiquitin binding
GO:0032312 IEA regulation of ARF GTPase activity
GO:0034614 IEA cellular response to reactive oxygen species
GO:0043161 IEA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0071944 IEA cell periphery

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087822 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 protein_coding Danio_rerio
ENSMUSG00000023353 Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 protein_coding Mus_musculus

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