C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000024123 Agap3-201 ENSMUSG00000023353 10090 + 5:24452177-24502047 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000024123
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000024123 9.002±2.63 13.329±3.14 14.092±3.42 24.282±11.05 11.676±5.87 10.169±1.38 5.290±2.51 6.170±2.92 4.293±1.91 19.105±3.05 2.328±0.94 19.647±8.33 13.111±6.54 3.325±1.63

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008T1 CIL_0008T1_0002 VISTA 5:24041638-24646055
CIL_0007RX CIL_0007RX_0002 VISTA 5:24430554-25031843
CIL_0003TG CIL_0003TG_0002 CGP 5:24445458-24502047
CIL_0004EO CIL_0004EO_0002 CGP 5:24452177-24527202

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000060 IMP protein import into nucleus, translocation
GO:0003924 IDA GTPase activity
GO:0005525 IEA GTP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006184 IEA GTP catabolic process
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008060 IEA ARF GTPase activator activity
GO:0008270 IEA zinc ion binding
GO:0016020 IEA membrane
GO:0016605 ISO PML body
GO:0030578 ISO PML body organization
GO:0031593 IDA polyubiquitin binding
GO:0032312 IEA regulation of ARF GTPase activity
GO:0034614 IDA cellular response to reactive oxygen species
GO:0034644 ISO cellular response to UV
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043547 IEA positive regulation of GTPase activity
GO:0071944 IDA cell periphery

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000125104 agap2-202 protein_coding Danio_rerio 0.000004 58
ENSDART00000086813 agap2-201 protein_coding Danio_rerio 0.000004 58
ENST00000304032 AGAP1-001 protein_coding Homo_sapiens 0 664
ENST00000335367 AGAP3-005 protein_coding Homo_sapiens 0 1092
ENST00000336665 AGAP1-002 protein_coding Homo_sapiens 0 664
ENST00000397238 AGAP3-001 protein_coding Homo_sapiens 0 3493
ENST00000409457 AGAP1-003 protein_coding Homo_sapiens 0 558
ENST00000461065 AGAP3-007 protein_coding Homo_sapiens 0 1347
ENST00000463179 AGAP3-020 retained_intron Homo_sapiens 1e-24 117
ENST00000463381 AGAP3-002 protein_coding Homo_sapiens 0 1552
ENST00000467250 AGAP3-026 processed_transcript Homo_sapiens 2e-21 106
ENST00000467724 AGAP3-015 nonsense_mediated_decay Homo_sapiens 0 592
ENST00000468796 AGAP3-016 protein_coding Homo_sapiens 0 560
ENST00000469901 AGAP3-010 protein_coding Homo_sapiens 0 608
ENST00000473140 AGAP3-013 retained_intron Homo_sapiens 0 405
ENST00000473312 AGAP3-004 protein_coding Homo_sapiens 0 1509
ENST00000473633 AGAP3-008 retained_intron Homo_sapiens 0 1127
ENST00000475145 AGAP3-025 processed_transcript Homo_sapiens 0 213
ENST00000476375 AGAP3-011 processed_transcript Homo_sapiens 0 684
ENST00000478320 AGAP3-023 processed_transcript Homo_sapiens 0 346
ENST00000479901 AGAP3-003 protein_coding Homo_sapiens 0 1266
ENST00000480106 AGAP3-017 processed_transcript Homo_sapiens 0 407
ENST00000483971 AGAP3-024 processed_transcript Homo_sapiens 2e-24 115
ENST00000485904 AGAP3-021 processed_transcript Homo_sapiens 0 625
ENST00000486946 AGAP3-019 processed_transcript Homo_sapiens 0 250
ENST00000490097 AGAP3-009 processed_transcript Homo_sapiens 0 532
ENST00000490839 AGAP3-014 retained_intron Homo_sapiens 0 316
ENST00000492234 AGAP3-012 processed_transcript Homo_sapiens 0 664
ENST00000494808 AGAP3-022 retained_intron Homo_sapiens 0 294
ENST00000498559 AGAP3-018 retained_intron Homo_sapiens 0 514
ENST00000622464 AGAP3-201 protein_coding Homo_sapiens 0 3343

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