C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box P4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000023991 Foxp4 10090 - 17:47867133-47924645 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000097311 Foxp4-002 47867764-47924435 protein_coding
  ENSMUST00000113262 Foxp4-003 47867768-47924476 protein_coding
  ENSMUST00000113263 Foxp4-008 47867764-47924400 protein_coding
  ENSMUST00000113265 Foxp4-001 47867133-47924645 protein_coding
  ENSMUST00000136314 Foxp4-005 47878285-47888433 processed_transcript
  ENSMUST00000137039 Foxp4-006 47880340-47888150 retained_intron
  ENSMUST00000153752 Foxp4-004 47887893-47924426 retained_intron
  ENSMUST00000154108 Foxp4-007 47878480-47878953 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000097311ENSMUST00000113262ENSMUST00000113263ENSMUST00000113265
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000097311 N/A N/A 2.353±0.44 4.489±0.00 6.254±0.00 6.111±0.29 N/A N/A 1.088±0.07 N/A 0.425±0.17 6.040±0.38 9.629±4.20 N/A
ENSMUST00000113262 8.617±2.28 9.001±0.52 5.071±0.82 8.223±4.97 14.499±7.18 22.961±6.22 2.674±0.83 5.233±0.36 5.529±0.91 16.500±3.82 1.314±0.44 19.429±8.17 9.774±4.42 1.745±0.37
ENSMUST00000113263 1.916±0.19 2.687±0.28 N/A 13.075±0.00 N/A 7.192±0.00 0.643±0.10 1.039±0.05 N/A 3.147±0.00 N/A 8.289±1.30 17.300±6.40 0.988±0.85
ENSMUST00000113265 2.957±1.05 3.151±0.39 4.423±1.12 7.718±0.17 6.643±2.17 8.516±1.51 0.980±0.00 1.402±0.25 1.768±0.76 5.980±2.07 0.445±0.24 7.160±1.15 8.347±0.41 0.375±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000963 CIL_000963_0002 VISTA 17:47571879-48173076
CIL_00093V CIL_00093V_0002 VISTA 17:47614773-48215356
CIL_0008XI CIL_0008XI_0002 VISTA 17:47688296-48291797
CIL_0008IB CIL_0008IB_0002 VISTA 17:47708185-48309224
CIL_0007QG CIL_0007QG_0002 VISTA 17:47710565-48311720
CIL_0008F3 CIL_0008F3_0002 VISTA 17:47757242-48358147

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007507 IMP heart development
GO:0042803 IPI protein homodimerization activity
GO:0043565 IEA sequence-specific DNA binding
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity
GO:0048617 IMP embryonic foregut morphogenesis
GO:0061140 IGI lung secretory cell differentiation
GO:1901249 IGI regulation of lung goblet cell differentiation
GO:1901250 IGI negative regulation of lung goblet cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076120 foxp4 forkhead box P4 protein_coding Danio_rerio
ENSG00000137166 FOXP4 forkhead box P4 protein_coding Homo_sapiens

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