C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neurexin I
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024109 Nrxn1 10090 - 17:90033644-91092805 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000054059 Nrxn1-020 90037077-91088726 protein_coding
  ENSMUST00000072671 Nrxn1-002 90037077-91088726 protein_coding
  ENSMUST00000159419 Nrxn1-003 90703176-91092791 retained_intron
  ENSMUST00000159778 Nrxn1-009 90036900-91092803 protein_coding
  ENSMUST00000160467 Nrxn1-006 90699931-91092736 retained_intron
  ENSMUST00000160800 Nrxn1-014 90036896-91092733 protein_coding
  ENSMUST00000160844 Nrxn1-001 90033644-91092805 protein_coding
  ENSMUST00000161102 Nrxn1-013 90208288-91092803 retained_intron
  ENSMUST00000161402 Nrxn1-011 90037077-91088726 protein_coding
  ENSMUST00000161637 Nrxn1-004 90535206-91088483 processed_transcript
  ENSMUST00000162002 Nrxn1-007 91085458-91092753 retained_intron
  ENSMUST00000162227 Nrxn1-008 90620803-90630027 retained_intron
  ENSMUST00000172466 Nrxn1-017 90037077-90455886 protein_coding
  ENSMUST00000173222 Nrxn1-005 90036853-90088140 processed_transcript
  ENSMUST00000173917 Nrxn1-010 90036966-90088363 protein_coding
  ENSMUST00000174331 Nrxn1-015 90037077-91088726 protein_coding
  ENSMUST00000174337 Nrxn1-016 90037077-90455872 protein_coding
  ENSMUST00000176118 Nrxn1-012 90362794-90588842 protein_coding
  ENSMUST00000176918 Nrxn1-019 90162305-90349360 processed_transcript
  ENSMUST00000177342 Nrxn1-018 90589916-90623544 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054059ENSMUST00000072671ENSMUST00000159419ENSMUST00000160467ENSMUST00000160844ENSMUST00000161102ENSMUST00000161402ENSMUST00000161637ENSMUST00000172466ENSMUST00000173917ENSMUST00000174331ENSMUST00000174337ENSMUST00000176118ENSMUST00000176918ENSMUST00000177342
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054059 0.331±0.14 1.241±0.35 N/A 15.795±0.00 0.239±0.13 0.399±0.11 0.249±0.15 0.028±0.02 0.432±0.30 0.399±0.21 N/A 0.834±0.48 N/A N/A
ENSMUST00000072671 0.216±0.01 1.238±0.48 N/A N/A 0.216±0.18 N/A 0.194±0.08 0.024±0.01 0.317±0.17 0.530±0.30 N/A 0.768±0.39 N/A 0.668±0.17
ENSMUST00000159419 N/A N/A N/A N/A N/A N/A N/A 0.038±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000160467 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.025±0.00 N/A
ENSMUST00000160844 0.078±0.02 N/A N/A 12.638±9.36 0.058±0.03 N/A 0.030±0.00 0.022±0.00 0.114±0.06 0.087±0.00 0.010±0.00 N/A 0.004±0.00 N/A
ENSMUST00000161102 N/A N/A 0.025±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.558±0.00 N/A N/A
ENSMUST00000161402 N/A N/A N/A N/A 0.462±0.00 N/A N/A N/A 0.436±0.21 N/A N/A N/A N/A N/A
ENSMUST00000161637 N/A N/A 0.037±0.00 N/A N/A N/A N/A 0.056±0.00 N/A N/A 0.016±0.00 N/A N/A 0.859±0.03
ENSMUST00000172466 0.169±0.05 N/A N/A N/A 0.110±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000173917 N/A N/A N/A 127.985±0.00 N/A 0.621±0.00 N/A N/A N/A N/A 0.096±0.00 N/A 0.134±0.01 N/A
ENSMUST00000174331 N/A N/A N/A 12.280±6.30 0.168±0.03 0.461±0.14 N/A 0.043±0.00 0.029±0.00 N/A N/A 0.651±0.23 0.004±0.00 N/A
ENSMUST00000174337 N/A N/A N/A N/A 0.155±0.00 N/A N/A N/A 0.085±0.00 N/A 0.015±0.00 N/A N/A N/A
ENSMUST00000176118 N/A N/A N/A N/A N/A N/A N/A 0.151±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000176918 N/A N/A N/A N/A N/A N/A N/A 0.485±0.02 N/A N/A N/A N/A N/A N/A
ENSMUST00000177342 N/A N/A N/A N/A 0.644±0.00 N/A N/A N/A N/A N/A N/A N/A 0.094±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0005246 IGI calcium channel regulator activity
GO:0005509 ISS calcium ion binding
GO:0005515 IPI protein binding
GO:0005886 ISS plasma membrane
GO:0007155 IEA cell adhesion
GO:0007157 IDA heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007158 IDA neuron cell-cell adhesion
GO:0007268 IGI synaptic transmission
GO:0007269 IGI neurotransmitter secretion
GO:0007416 IGI synapse assembly
GO:0007612 IMP learning
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0016339 IDA calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0021707 IGI cerebellar granule cell differentiation
GO:0030054 IEA cell junction
GO:0030139 ISS endocytic vesicle
GO:0030534 IMP adult behavior
GO:0033130 IDA acetylcholine receptor binding
GO:0035176 IEA social behavior
GO:0035418 IDA protein localization to synapse
GO:0042297 IEA vocal learning
GO:0042551 IDA neuron maturation
GO:0042734 IDA presynaptic membrane
GO:0044295 IDA axonal growth cone
GO:0045184 IDA establishment of protein localization
GO:0046872 IEA metal ion binding
GO:0048306 IDA calcium-dependent protein binding
GO:0050839 IPI cell adhesion molecule binding
GO:0050885 IMP neuromuscular process controlling balance
GO:0051490 IDA negative regulation of filopodium assembly
GO:0051965 IGI positive regulation of synapse assembly
GO:0051968 IMP positive regulation of synaptic transmission, glutamatergic
GO:0060076 IC excitatory synapse
GO:0060077 IC inhibitory synapse
GO:0060134 IMP prepulse inhibition
GO:0061178 IMP regulation of insulin secretion involved in cellular response to glucose stimulus
GO:0071625 IEA vocalization behavior
GO:0090004 IDA positive regulation of establishment of protein localization to plasma membrane
GO:0090129 IDA positive regulation of synapse maturation
GO:0097091 IDA synaptic vesicle clustering
GO:0097104 IDA postsynaptic membrane assembly
GO:0097105 IDA presynaptic membrane assembly
GO:0097109 IPI neuroligin family protein binding
GO:0097112 IDA gamma-aminobutyric acid receptor clustering
GO:0097114 IDA N-methyl-D-aspartate receptor clustering
GO:0097116 IDA gephyrin clustering
GO:0097117 IDA guanylate kinase-associated protein clustering
GO:0097118 IDA neuroligin clustering
GO:0097119 IDA postsynaptic density protein 95 clustering
GO:0097120 IDA receptor localization to synapse
GO:2000310 IDA regulation of N-methyl-D-aspartate selective glutamate receptor activity
GO:2000311 IDA regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463 IMP positive regulation of excitatory postsynaptic membrane potential
GO:2000821 IMP regulation of grooming behavior

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063150 nrxn2b neurexin 2b protein_coding Danio_rerio
ENSG00000179915 NRXN1 neurexin 1 protein_coding Homo_sapiens

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