C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histocompatibility 2, O region alpha locus
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024334 H2-Oa 10090 + 17:34092340-34095234 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025192 H2-Oa-001 34092340-34095234 protein_coding
  ENSMUST00000174670 H2-Oa-002 34092422-34095233 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025192ENSMUST00000174670
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025192 1.654±1.12 0.799±0.22 0.850±0.20 0.076±0.05 27.891±12.30 3.911±0.29 0.522±0.43 1.978±0.93 0.501±0.17 6.205±0.70 1.206±1.60 1.842±0.56 0.153±0.10 0.068±0.03
ENSMUST00000174670 0.186±0.12 0.492±0.00 0.064±0.00 0.009±0.00 5.750±3.21 0.754±0.23 0.202±0.09 0.305±0.15 0.074±0.00 1.102±0.23 0.371±0.00 0.322±0.14 0.092±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002587 IEA negative regulation of antigen processing and presentation of peptide antigen via MHC class II
GO:0006955 IEA immune response
GO:0016021 IEA integral component of membrane
GO:0019882 IMP antigen processing and presentation
GO:0019886 IMP antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IEA MHC class II protein complex binding
GO:0045580 IMP regulation of T cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000001832 si:ch1073-403i13.1 si:ch1073-403i13.1 protein_coding Danio_rerio
ENSDARG00000020286 zgc:123107 zgc:123107 protein_coding Danio_rerio
ENSDARG00000031745 si:busm1-266f07.2 si:busm1-266f07.2 protein_coding Danio_rerio
ENSDARG00000053739 si:busm1-160c18.1 si:busm1-160c18.1 protein_coding Danio_rerio
ENSDARG00000055441 si:busm1-48c11.3 si:busm1-48c11.3 protein_coding Danio_rerio
ENSDARG00000070206 si:zfos-2070c2.1 si:zfos-2070c2.1 protein_coding Danio_rerio
ENSDARG00000074816 si:zfos-367g9.1 si:zfos-367g9.1 protein_coding Danio_rerio
ENSDARG00000075932 si:ch73-211l2.3 si:ch73-211l2.3 protein_coding Danio_rerio
ENSDARG00000079593 si:busm1-228j01.5 si:busm1-228j01.5 protein_coding Danio_rerio
ENSDARG00000086294 CU914776.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000204252 HLA-DOA major histocompatibility complex, class II, DO alpha protein_coding Homo_sapiens

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