C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane protein 173
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024349 Tmem173 10090 - 18:35733678-35740554 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000115728 Tmem173-201 35733678-35740554 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000115728
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000115728 11.656±2.92 3.425±0.59 5.359±1.19 0.621±0.20 23.253±5.20 7.645±1.34 3.029±0.81 3.083±0.23 2.015±0.96 9.349±0.56 1.131±0.74 9.624±3.46 1.559±0.96 0.314±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000547 CIL_000547_0002 CGP 18:35713086-35740554
CIL_000548 CIL_000548_0002 CGP 18:35733678-35807172

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002218 IMP activation of innate immune response
GO:0002230 IEA positive regulation of defense response to virus by host
GO:0005515 IPI protein binding
GO:0005741 IEA mitochondrial outer membrane
GO:0005777 IDA peroxisome
GO:0005783 IDA endoplasmic reticulum
GO:0005789 ISS endoplasmic reticulum membrane
GO:0005794 IDA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006915 IEA apoptotic process
GO:0008134 IEA transcription factor binding
GO:0016021 IEA integral component of membrane
GO:0019901 IEA protein kinase binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032092 IEA positive regulation of protein binding
GO:0032481 IEA positive regulation of type I interferon production
GO:0032608 ISS interferon-beta production
GO:0033160 IEA positive regulation of protein import into nucleus, translocation
GO:0035438 IDA cyclic-di-GMP binding
GO:0035458 IMP cellular response to interferon-beta
GO:0042802 IEA identical protein binding
GO:0042803 ISS protein homodimerization activity
GO:0042993 IEA positive regulation of transcription factor import into nucleus
GO:0045087 ISS innate immune response
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051607 ISS defense response to virus
GO:0061507 IDA cyclic-GMP-AMP binding
GO:0071360 IEA cellular response to exogenous dsRNA

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091058 tmem173 transmembrane protein 173 protein_coding Danio_rerio
ENSG00000184584 TMEM173 transmembrane protein 173 protein_coding Homo_sapiens

Loading