C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transmembrane protein 173
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184584 TMEM173 9606 - 5:139475534-139482935 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000330794 TMEM173-001 139475964-139482790 protein_coding
  ENST00000502362 TMEM173-007 139481246-139482310 retained_intron
  ENST00000502825 TMEM173-013 139477483-139481087 retained_intron
  ENST00000503287 TMEM173-010 139476345-139481461 retained_intron
  ENST00000503838 TMEM173-012 139479170-139481349 retained_intron
  ENST00000507297 TMEM173-002 139475534-139482698 retained_intron
  ENST00000509573 TMEM173-014 139476026-139481368 retained_intron
  ENST00000510817 TMEM173-006 139478270-139482351 protein_coding
  ENST00000511850 TMEM173-011 139478462-139482296 processed_transcript
  ENST00000511886 TMEM173-008 139477455-139482689 processed_transcript
  ENST00000512606 TMEM173-015 139476301-139481629 processed_transcript
  ENST00000514119 TMEM173-005 139478352-139482758 retained_intron
  ENST00000514348 TMEM173-003 139481419-139482935 retained_intron
  ENST00000514542 TMEM173-004 139481846-139482720 processed_transcript
  ENST00000515507 TMEM173-016 139478368-139482310 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000330794ENST00000502825ENST00000503287ENST00000507297ENST00000509573ENST00000510817ENST00000511886ENST00000512606ENST00000514119ENST00000515507
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000330794 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.343±0.00 N/A
ENST00000502825 N/A N/A N/A 2.339±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000503287 N/A N/A N/A N/A N/A N/A 0.645±0.00 N/A N/A N/A 8.044±6.76 18.444±0.00 3.580±0.00
ENST00000507297 N/A 11.832±0.00 0.196±0.00 2.333±0.00 0.080±0.00 N/A N/A N/A N/A 0.171±0.00 2.586±0.00 N/A N/A
ENST00000509573 N/A N/A N/A N/A N/A N/A N/A 1.241±0.00 58.025±0.00 N/A N/A N/A N/A
ENST00000510817 N/A N/A N/A N/A 0.777±0.00 N/A N/A N/A 2.334±0.00 N/A N/A N/A N/A
ENST00000511886 13.311±0.00 N/A N/A N/A N/A 8.078±5.57 N/A N/A N/A N/A N/A N/A N/A
ENST00000512606 N/A N/A N/A 1.732±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000514119 N/A N/A N/A N/A N/A 0.922±0.00 1.296±0.00 2.625±0.00 1.842±0.00 N/A N/A N/A N/A
ENST00000515507 N/A N/A N/A N/A N/A N/A 0.751±0.00 N/A N/A N/A 1.585±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000547 CIL_000547_0001 CGP 5:139448556-139482935
CIL_000548 CIL_000548_0001 CGP 5:139475534-139628433

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002218 IMP activation of innate immune response
GO:0002230 IMP positive regulation of defense response to virus by host
GO:0005515 IPI protein binding
GO:0005741 IDA mitochondrial outer membrane
GO:0005777 IEA peroxisome
GO:0005783 IEA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0006915 IEA apoptotic process
GO:0008134 IDA transcription factor binding
GO:0016021 IEA integral component of membrane
GO:0019901 IDA protein kinase binding
GO:0030659 TAS cytoplasmic vesicle membrane
GO:0031625 IEA ubiquitin protein ligase binding
GO:0032092 IDA positive regulation of protein binding
GO:0032479 TAS regulation of type I interferon production
GO:0032481 IEA:TAS positive regulation of type I interferon production
GO:0032608 IMP interferon-beta production
GO:0033160 IDA positive regulation of protein import into nucleus, translocation
GO:0035438 IDA cyclic-di-GMP binding
GO:0035458 IEA cellular response to interferon-beta
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0042993 IDA positive regulation of transcription factor import into nucleus
GO:0045087 IMP innate immune response
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051607 IDA defense response to virus
GO:0061507 ISS cyclic-GMP-AMP binding
GO:0071360 IMP cellular response to exogenous dsRNA

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000091058 tmem173 transmembrane protein 173 protein_coding Danio_rerio
ENSMUSG00000024349 Tmem173 transmembrane protein 173 protein_coding Mus_musculus

Loading