C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phorbol-12-myristate-13-acetate-induced protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024521 Pmaip1 10090 + 18:66458604-66465550 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025399 Pmaip1-201 66458604-66465550 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025399
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025399 1.200±0.94 0.311±0.16 1.983±0.21 0.479±0.28 1.882±1.28 7.431±2.34 0.075±0.03 3.715±0.56 0.498±0.41 3.062±0.14 0.068±0.08 0.703±0.30 4.516±2.28 0.540±0.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007FI CIL_0007FI_0002 CGP 18:66045302-66465550
CIL_0007FH CIL_0007FH_0002 CGP 18:66458604-66860472

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001836 IMP release of cytochrome c from mitochondria
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005739 IDA mitochondrion
GO:0005829 IEA cytosol
GO:0006915 IEA apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009411 IMP response to UV
GO:0010165 IMP response to X-ray
GO:0010498 IEA proteasomal protein catabolic process
GO:0010907 IEA positive regulation of glucose metabolic process
GO:0010917 IDA negative regulation of mitochondrial membrane potential
GO:0032461 IEA positive regulation of protein oligomerization
GO:0042149 IEA cellular response to glucose starvation
GO:0042771 IDA intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0042981 RCA regulation of apoptotic process
GO:0043029 IMP T cell homeostasis
GO:0043065 IMP positive regulation of apoptotic process
GO:0043280 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043331 IEA response to dsRNA
GO:0043517 IMP positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043525 IMP positive regulation of neuron apoptotic process
GO:0046902 IEA regulation of mitochondrial membrane permeability
GO:0048147 IMP negative regulation of fibroblast proliferation
GO:0051607 IEA defense response to virus
GO:0071456 IEA cellular response to hypoxia
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator
GO:0072593 IEA reactive oxygen species metabolic process
GO:0090200 IEA positive regulation of release of cytochrome c from mitochondria
GO:0097193 IEA intrinsic apoptotic signaling pathway
GO:1900740 IMP positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1902043 IEA positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001244 IEA positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000141682 PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 protein_coding Homo_sapiens

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