C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transducin-like enhancer of split 4, homolog of Drosophila E(spl)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024642 Tle4 10090 - 19:14448072-14598051 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000052011 Tle4-201 14448072-14597983 protein_coding
  ENSMUST00000167776 Tle4-202 14448150-14598051 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000052011ENSMUST00000167776
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000052011 3.554±0.98 3.515±1.12 2.721±0.65 7.101±0.89 5.906±2.60 18.679±0.73 2.669±0.57 5.795±0.34 2.767±0.94 9.154±1.19 2.801±0.76 4.671±2.25 2.210±0.86 1.595±0.60
ENSMUST00000167776 N/A 4.823±0.00 0.772±0.23 3.489±2.07 N/A N/A 0.323±0.00 N/A 0.571±0.19 N/A 0.897±0.40 3.117±0.00 0.971±0.61 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007XU CIL_0007XU_0002 VISTA 19:13939310-14542197
CIL_0007KE CIL_0007KE_0003 UCNEbase 19:14123720-15837295
CIL_0008CI CIL_0008CI_0002 VISTA 19:14206310-14808632
CIL_0007V5 CIL_0007V5_0002 VISTA 19:14208410-14810921
CIL_0009BM CIL_0009BM_0002 VISTA 19:14218112-14819083
CIL_00087P CIL_00087P_0002 VISTA 19:14240262-14842406
CIL_0009CZ CIL_0009CZ_0002 VISTA 19:14265295-14868168
CIL_0009CX CIL_0009CX_0002 VISTA 19:14358815-14960520

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003682 IDA chromatin binding
GO:0003705 IGI RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0006366 IGI transcription from RNA polymerase II promoter
GO:0016055 IDA Wnt signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0070491 IPI repressing transcription factor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000106829 TLE4 transducin-like enhancer of split 4 protein_coding Homo_sapiens

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