C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: transducin-like enhancer of split 4, homolog of Drosophila E(spl)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000052011 Tle4-201 ENSMUSG00000024642 10090 - 19:14448072-14597983 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000052011
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000052011 3.554±0.98 3.515±1.12 2.721±0.65 7.101±0.89 5.906±2.60 18.679±0.73 2.669±0.57 5.795±0.34 2.767±0.94 9.154±1.19 2.801±0.76 4.671±2.25 2.210±0.86 1.595±0.60

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007XU CIL_0007XU_0002 VISTA 19:13939310-14542197
CIL_0007KE CIL_0007KE_0003 UCNEbase 19:14123720-15837295
CIL_0008CI CIL_0008CI_0002 VISTA 19:14206310-14808632
CIL_0007V5 CIL_0007V5_0002 VISTA 19:14208410-14810921
CIL_0009BM CIL_0009BM_0002 VISTA 19:14218112-14819083
CIL_00087P CIL_00087P_0002 VISTA 19:14240262-14842406
CIL_0009CZ CIL_0009CZ_0002 VISTA 19:14265295-14868168
CIL_0009CX CIL_0009CX_0002 VISTA 19:14358815-14960520

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003682 IDA chromatin binding
GO:0003705 IGI RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0006366 IGI transcription from RNA polymerase II promoter
GO:0016055 IDA Wnt signaling pathway
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0070491 IPI repressing transcription factor binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000100633 gro2-203 protein_coding Danio_rerio 0 802
ENSDART00000025018 gro2-201 protein_coding Danio_rerio 0 802
ENSDART00000100632 gro2-202 protein_coding Danio_rerio 0 802
ENSDART00000045679 gro2-001 protein_coding Danio_rerio 0 802
ENSDART00000127222 aes-202 protein_coding Danio_rerio 0 248
ENSDART00000105564 aes-201 protein_coding Danio_rerio 0 248
ENST00000265284 TLE4-018 protein_coding Homo_sapiens 0 2723
ENST00000376472 TLE1-201 protein_coding Homo_sapiens 0 1448
ENST00000376499 TLE1-001 protein_coding Homo_sapiens 0 1463
ENST00000376524 TLE4-019 processed_transcript Homo_sapiens 0 479
ENST00000376525 TLE4-012 retained_intron Homo_sapiens 0 401
ENST00000376537 TLE4-015 protein_coding Homo_sapiens 0 2121
ENST00000376544 TLE4-201 protein_coding Homo_sapiens 0 3714
ENST00000376552 TLE4-008 protein_coding Homo_sapiens 0 3773
ENST00000414465 TLE4-004 protein_coding Homo_sapiens 0 401
ENST00000417836 TLE4-029 protein_coding Homo_sapiens 0 527
ENST00000425506 TLE4-009 protein_coding Homo_sapiens 0 857
ENST00000428713 TLE4-003 protein_coding Homo_sapiens 0 1114
ENST00000435650 TLE4-006 protein_coding Homo_sapiens 0 701
ENST00000440700 RP11-79D8.2-001 processed_pseudogene Homo_sapiens 0 281
ENST00000455913 TLE4-007 processed_transcript Homo_sapiens 0 686
ENST00000461758 TLE4-013 nonsense_mediated_decay Homo_sapiens 0 481
ENST00000462803 TLE4-016 nonsense_mediated_decay Homo_sapiens 0 2543
ENST00000466428 TLE4-021 retained_intron Homo_sapiens 0 579
ENST00000467142 TLE4-028 protein_coding Homo_sapiens 0 494
ENST00000470872 TLE4-014 nonsense_mediated_decay Homo_sapiens 0 3081
ENST00000474519 TLE4-023 processed_transcript Homo_sapiens 8.00001e-41 171
ENST00000476523 TLE4-020 processed_transcript Homo_sapiens 0 409
ENST00000478290 TLE4-005 processed_transcript Homo_sapiens 0 656
ENST00000483597 TLE4-024 processed_transcript Homo_sapiens 2e-32 143
ENST00000485159 TLE4-010 retained_intron Homo_sapiens 0 579
ENST00000490347 TLE4-025 protein_coding Homo_sapiens 0 538
ENST00000493163 TLE4-001 processed_transcript Homo_sapiens 0 189
ENST00000495170 TLE4-027 retained_intron Homo_sapiens 0 582
ENST00000496114 TLE4-030 protein_coding Homo_sapiens 0 926
ENST00000496853 TLE4-022 processed_transcript Homo_sapiens 0 407

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