C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: estrogen related receptor, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024955 Esrra 10090 - 19:6910977-6921813 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025906 Esrra-001 6910977-6921808 protein_coding
  ENSMUST00000145192 Esrra-003 6919905-6921767 retained_intron
  ENSMUST00000172975 Esrra-002 6920079-6921051 protein_coding
  ENSMUST00000173308 Esrra-004 6912765-6921813 processed_transcript
  ENSMUST00000173635 Esrra-005 6912452-6921761 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025906ENSMUST00000145192ENSMUST00000173635
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025906 18.642±3.52 24.988±7.86 27.192±8.84 12.836±1.29 26.569±3.15 87.421±12.83 44.398±4.11 55.493±2.58 12.180±2.12 16.008±2.04 35.357±11.28 16.313±1.11 16.279±1.34 7.136±0.34
ENSMUST00000145192 N/A 39.907±0.32 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000173635 N/A N/A N/A N/A N/A 72.132±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0005496 IEA steroid binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005730 IEA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0015630 IEA microtubule cytoskeleton
GO:0019904 IEA protein domain specific binding
GO:0030278 IEA regulation of ossification
GO:0042127 IEA regulation of cell proliferation
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA:ISS sequence-specific DNA binding
GO:0045171 IEA intercellular bridge
GO:0045667 IEA regulation of osteoblast differentiation
GO:0045670 IEA regulation of osteoclast differentiation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051216 IEA cartilage development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069266 esrra estrogen-related receptor alpha protein_coding Danio_rerio
ENSG00000173153 ESRRA estrogen-related receptor alpha protein_coding Homo_sapiens

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