C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: STE20-like kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025060 Slk 10090 + 19:47579678-47645246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026043 Slk-001 47579678-47645246 protein_coding
  ENSMUST00000051691 Slk-002 47580019-47642455 protein_coding
  ENSMUST00000123816 Slk-003 47620670-47625354 retained_intron
  ENSMUST00000130115 Slk-005 47622658-47625854 retained_intron
  ENSMUST00000147841 Slk-004 47635130-47636454 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026043ENSMUST00000051691
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026043 5.092±2.90 16.421±0.95 6.660±1.28 2.823±1.23 9.040±0.45 5.546±2.73 2.167±0.27 9.396±4.08 10.430±4.50 5.231±0.80 8.416±1.86 8.383±2.86 1.642±0.74
ENSMUST00000051691 N/A N/A 13.920±0.00 N/A N/A N/A N/A 2.496±0.65 N/A N/A 7.388±4.89 22.411±14.38 4.259±5.47

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000663 CIL_000663_0002 CGP 19:47501033-47645246
CIL_0006FI CIL_0006FI_0002 CGP 19:47579678-47692094

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006915 IEA apoptotic process
GO:0042802 IEA identical protein binding
GO:0042803 ISS protein homodimerization activity
GO:0046777 ISS protein autophosphorylation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012574 slkb STE20-like kinase b protein_coding Danio_rerio
ENSDARG00000061525 slka STE20-like kinase a protein_coding Danio_rerio
ENSG00000065613 SLK STE20-like kinase protein_coding Homo_sapiens

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