C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FYVE, RhoGEF and PH domain containing 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000026296 Fgd1-001 ENSMUSG00000025265 10090 + X:151047170-151089521 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000026296
Transcript ID Adipose Bladder Brain Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000026296 1.027±0.00 2.710±0.00 5.911±2.85 0.705±0.14 0.948±0.00 1.048±0.24 1.841±0.30 0.547±0.07 2.356±0.28 4.668±0.00 0.388±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001726 IDA ruffle
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005856 IEA cytoskeleton
GO:0007010 IDA cytoskeleton organization
GO:0008360 IDA regulation of cell shape
GO:0030027 IDA lamellipodium
GO:0030036 IEA actin cytoskeleton organization
GO:0031267 IEA small GTPase binding
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0043088 IEA regulation of Cdc42 GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0046847 IEA filopodium assembly
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000274963 FGD2-001 protein_coding Homo_sapiens 0.00000009 64
ENST00000337352 FGD3-201 protein_coding Homo_sapiens 0 381
ENST00000373535 FGD2-003 nonsense_mediated_decay Homo_sapiens 0.00000007 64
ENST00000375135 FGD1-001 protein_coding Homo_sapiens 0 4935
ENST00000375482 FGD3-001 protein_coding Homo_sapiens 0 381
ENST00000416701 FGD3-202 protein_coding Homo_sapiens 0 381
ENST00000464083 FGD2-006 retained_intron Homo_sapiens 0.00000008 64
ENST00000467786 FGD3-002 nonsense_mediated_decay Homo_sapiens 0 381
ENST00000487920 FGD2-010 retained_intron Homo_sapiens 0.00000008 64
ENST00000493635 FGD2-009 retained_intron Homo_sapiens 0.0000002 64
ENST00000494343 FGD2-007 retained_intron Homo_sapiens 0.00000009 64

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