C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: membrane-associated ring finger (C3HC4) 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025702 March8 10090 + 6:116338024-116409540 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000079012 March8-001 116338024-116409540 protein_coding
  ENSMUST00000101032 March8-002 116338033-116409540 protein_coding
  ENSMUST00000123246 March8-007 116386250-116406134 retained_intron
  ENSMUST00000123405 March8-009 116401583-116406356 retained_intron
  ENSMUST00000126376 March8-003 116338064-116376802 processed_transcript
  ENSMUST00000127992 March8-008 116338034-116401982 retained_intron
  ENSMUST00000129170 March8-004 116350933-116376863 processed_transcript
  ENSMUST00000130445 March8-010 116376693-116401431 retained_intron
  ENSMUST00000135901 March8-006 116386224-116406224 protein_coding
  ENSMUST00000140884 March8-005 116350892-116401122 processed_transcript
  ENSMUST00000156014 March8-011 116402992-116405782 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000079012ENSMUST00000101032ENSMUST00000135901
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000079012 7.199±1.28 9.774±3.82 9.508±1.56 8.266±4.18 10.775±5.18 5.019±0.55 3.008±1.29 15.431±3.07 12.762±6.24 6.283±0.49 2.201±0.84 10.891±5.72 4.977±2.65 2.573±1.28
ENSMUST00000101032 13.938±3.15 26.783±4.92 9.898±0.05 13.033±1.91 10.987±3.02 21.644±3.17 5.255±1.28 22.723±4.07 13.840±3.98 14.468±0.73 5.415±1.83 26.691±10.49 7.168±4.43 1.820±0.34
ENSMUST00000135901 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.567±0.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081B CIL_00081B_0002 VISTA 6:116052182-116663911

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000209 IEA protein polyubiquitination
GO:0002495 IDA antigen processing and presentation of peptide antigen via MHC class II
GO:0004842 ISS ubiquitin-protein transferase activity
GO:0005764 ISS lysosome
GO:0005768 ISS endosome
GO:0008270 IEA zinc ion binding
GO:0016021 IEA integral component of membrane
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031410 IEA cytoplasmic vesicle
GO:0042289 IPI MHC class II protein binding
GO:0045347 IDA negative regulation of MHC class II biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062489 march8 membrane-associated ring finger (C3HC4) 8 protein_coding Danio_rerio
ENSG00000165406 MARCH8 membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase protein_coding Homo_sapiens

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