C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, cAMP dependent regulatory, type I beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025855 Prkar1b 10090 - 5:139017306-139150001 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026973 Prkar1b-001 139017306-139129759 protein_coding
  ENSMUST00000110889 Prkar1b-003 139017317-139114054 protein_coding
  ENSMUST00000110890 Prkar1b-002 139017308-139130386 protein_coding
  ENSMUST00000129851 Prkar1b-006 139050662-139130159 protein_coding
  ENSMUST00000130180 Prkar1b-008 139148054-139149957 processed_transcript
  ENSMUST00000134762 Prkar1b-005 139108577-139130383 protein_coding
  ENSMUST00000139415 Prkar1b-010 139018666-139023810 processed_transcript
  ENSMUST00000141985 Prkar1b-009 139062596-139112644 protein_coding
  ENSMUST00000147505 Prkar1b-004 139108484-139130576 protein_coding
  ENSMUST00000148002 Prkar1b-011 139042451-139127805 protein_coding
  ENSMUST00000155833 Prkar1b-007 139108511-139150001 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungOvaryPlacentaTestisENSMUST00000026973ENSMUST00000110889ENSMUST00000147505ENSMUST00000148002
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Ovary Placenta Testis
ENSMUST00000026973 7.304±3.98 13.788±3.19 7.073±0.16 96.113±41.42 3.011±0.72 3.763±0.79 0.975±0.37 3.261±0.24 9.819±1.30 12.439±2.74 1.984±0.94 N/A
ENSMUST00000110889 N/A 9.312±1.02 N/A N/A N/A N/A N/A 2.456±0.00 N/A N/A N/A 4.406±0.00
ENSMUST00000147505 N/A N/A N/A 288.138±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000148002 N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.089±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00018I CIL_00018I_0002 CGP 5:138976014-139150001
CIL_00018H CIL_00018H_0002 CGP 5:139017306-139186510

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004862 IEA cAMP-dependent protein kinase inhibitor activity
GO:0005737 TAS cytoplasm
GO:0005886 IEA plasma membrane
GO:0005952 IEA cAMP-dependent protein kinase complex
GO:0006468 TAS protein phosphorylation
GO:0007611 IMP learning or memory
GO:0008283 TAS cell proliferation
GO:0008603 ISS cAMP-dependent protein kinase regulator activity
GO:0009887 TAS organ morphogenesis
GO:0030552 IEA cAMP binding
GO:0034236 IEA protein kinase A catalytic subunit binding
GO:2000480 IEA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062926 prkar1b protein kinase, cAMP-dependent, regulatory, type I, beta protein_coding Danio_rerio
ENSG00000188191 PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta protein_coding Homo_sapiens

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