C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase, cAMP-dependent, regulatory, type I, beta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188191 PRKAR1B 9606 - 7:549197-727650 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360274 PRKAR1B-001 549750-712572 protein_coding
  ENST00000400758 PRKAR1B-009 550270-602683 protein_coding
  ENST00000403562 PRKAR1B-002 549742-727650 protein_coding
  ENST00000406797 PRKAR1B-003 549198-713207 protein_coding
  ENST00000414568 PRKAR1B-010 596180-691794 protein_coding
  ENST00000417852 PRKAR1B-004 607396-727341 protein_coding
  ENST00000430040 PRKAR1B-008 579256-712940 protein_coding
  ENST00000456696 PRKAR1B-007 680556-713069 protein_coding
  ENST00000478198 PRKAR1B-006 716619-726977 processed_transcript
  ENST00000488474 PRKAR1B-005 696713-727237 processed_transcript
  ENST00000537384 PRKAR1B-201 549197-727341 protein_coding
  ENST00000544935 PRKAR1B-202 549197-712940 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000360274ENST00000400758ENST00000403562ENST00000414568ENST00000430040ENST00000537384
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000360274 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.483±0.00 N/A N/A N/A
ENST00000400758 N/A N/A N/A N/A N/A N/A N/A N/A 1.185±0.00 N/A N/A N/A N/A
ENST00000403562 N/A N/A 1.771±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000414568 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.334±0.00
ENST00000430040 2.923±0.00 N/A N/A 28.164±0.00 0.879±0.00 1.754±0.00 N/A 1.827±0.00 1.055±0.00 N/A 10.005±5.79 N/A 6.095±0.00
ENST00000537384 2.914±0.00 13.267±0.00 N/A 203.680±0.00 10.293±0.00 15.253±0.00 8.445±0.00 7.099±0.00 3.046±0.00 3.555±2.65 23.321±10.15 7.124±1.94 9.871±5.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00018I CIL_00018I_0001 CGP 7:497258-727650
CIL_00018H CIL_00018H_0001 CGP 7:549197-786475

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001932 IEA regulation of protein phosphorylation
GO:0004862 IDA cAMP-dependent protein kinase inhibitor activity
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005952 IEA:NAS cAMP-dependent protein kinase complex
GO:0006112 TAS energy reserve metabolic process
GO:0006468 NAS protein phosphorylation
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0007611 IEA learning or memory
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008603 IEA:NAS cAMP-dependent protein kinase regulator activity
GO:0030552 IEA cAMP binding
GO:0034199 TAS activation of protein kinase A activity
GO:0034236 IPI protein kinase A catalytic subunit binding
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0045859 IEA regulation of protein kinase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050796 TAS regulation of insulin secretion
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus
GO:2000480 IDA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062926 prkar1b protein kinase, cAMP-dependent, regulatory, type I, beta protein_coding Danio_rerio
ENSMUSG00000025855 Prkar1b protein kinase, cAMP dependent regulatory, type I beta protein_coding Mus_musculus

Loading