C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ARP3 actin-related protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026341 Actr3 10090 - 1:125392905-125435727 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027579 Actr3-201 125392905-125435727 protein_coding
  ENSMUST00000178474 Actr3-001 125392906-125435547 protein_coding
  ENSMUST00000185280 Actr3-007 125407358-125435470 protein_coding
  ENSMUST00000186008 Actr3-006 125393484-125397612 retained_intron
  ENSMUST00000187460 Actr3-003 125407349-125435707 protein_coding
  ENSMUST00000188362 Actr3-010 125396489-125398316 retained_intron
  ENSMUST00000188497 Actr3-002 125405880-125435727 protein_coding
  ENSMUST00000188827 Actr3-005 125416064-125435428 retained_intron
  ENSMUST00000189192 Actr3-009 125405861-125408941 retained_intron
  ENSMUST00000191004 Actr3-008 125407292-125435454 protein_coding
  ENSMUST00000191544 Actr3-004 125405910-125434646 protein_coding
  ENSMUST00000191578 Actr3-011 125393890-125435481 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027579ENSMUST00000178474ENSMUST00000186008ENSMUST00000188497ENSMUST00000191578
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027579 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.185±0.71 N/A 15.275±0.00 N/A
ENSMUST00000178474 10.183±1.93 17.450±9.59 49.659±0.95 11.949±0.56 6.260±0.58 11.223±2.31 7.766±1.77 8.948±4.69 24.890±18.74 14.530±1.87 9.710±3.73 8.100±1.19 49.343±21.79 N/A
ENSMUST00000186008 N/A N/A N/A 89.858±0.00 N/A N/A N/A N/A N/A N/A N/A 114.715±0.00 288.459±129.76 10.697±0.00
ENSMUST00000188497 16.019±5.30 30.395±9.91 N/A N/A 34.723±13.99 32.517±6.48 7.807±0.82 13.601±2.38 7.229±2.64 28.925±10.41 N/A 21.187±4.56 N/A 5.698±1.30
ENSMUST00000191578 17.800±6.39 N/A N/A 40.498±0.00 30.564±18.92 14.960±3.26 11.456±3.65 13.626±4.09 2.994±0.06 24.216±2.67 2.642±0.00 28.487±2.81 73.483±33.62 3.453±0.99

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0002102 IEA podosome
GO:0003779 IEA actin binding
GO:0005200 IEA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005884 IEA actin filament
GO:0005885 IEA Arp2/3 protein complex
GO:0005911 IDA cell-cell junction
GO:0005925 IEA focal adhesion
GO:0007163 IGI establishment or maintenance of cell polarity
GO:0008356 IGI asymmetric cell division
GO:0009743 IEA response to carbohydrate
GO:0010592 IEA positive regulation of lamellipodium assembly
GO:0016020 IEA membrane
GO:0016344 IGI meiotic chromosome movement towards spindle pole
GO:0030027 IDA lamellipodium
GO:0030056 IEA hemidesmosome
GO:0030838 IEA positive regulation of actin filament polymerization
GO:0031252 IEA cell leading edge
GO:0033206 IGI meiotic cytokinesis
GO:0034314 IEA Arp2/3 complex-mediated actin nucleation
GO:0043519 IEA regulation of myosin II filament organization
GO:0045666 IEA positive regulation of neuron differentiation
GO:0046677 IEA response to antibiotic
GO:0050775 IEA positive regulation of dendrite morphogenesis
GO:0051015 IEA actin filament binding
GO:0051321 IGI meiotic cell cycle
GO:0051491 IEA positive regulation of filopodium assembly
GO:0051653 IGI spindle localization
GO:0060076 IEA excitatory synapse
GO:0060271 ISS cilium morphogenesis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076772 ARP3 actin-related protein 3 homolog (yeast) protein_coding Danio_rerio
ENSDARG00000091138 ARP3 actin-related protein 3 homolog (yeast) protein_coding Danio_rerio
ENSG00000115091 ACTR3 ARP3 actin-related protein 3 homolog (yeast) protein_coding Homo_sapiens

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