C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ARP3 actin-related protein 3 homolog (yeast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115091 ACTR3 9606 + 2:113889960-113962596 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263238 ACTR3-001 113889960-113962596 protein_coding
  ENST00000415792 ACTR3-004 113890093-113940143 protein_coding
  ENST00000443297 ACTR3-003 113890063-113931369 protein_coding
  ENST00000446821 ACTR3-005 113890098-113942262 nonsense_mediated_decay
  ENST00000478928 ACTR3-002 113950824-113958589 retained_intron
  ENST00000484165 ACTR3-007 113933856-113940103 retained_intron
  ENST00000489779 ACTR3-006 113927369-113934640 retained_intron
  ENST00000535589 ACTR3-008 113890598-113957591 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263238ENST00000415792ENST00000478928ENST00000535589
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263238 9.293±0.00 11.196±0.00 2.201±0.00 6.555±0.07 6.635±0.78 8.559±0.67 1.808±0.31 3.370±0.15 4.469±3.69 6.793±2.47 1.809±1.25 9.050±3.74 4.832±2.48 7.304±1.84
ENST00000415792 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.671±0.00 N/A N/A N/A
ENST00000478928 N/A 2.743±0.00 1.045±0.00 N/A 2.526±1.01 3.531±0.00 0.813±0.00 N/A 2.671±0.00 3.353±0.00 0.229±0.00 5.347±0.00 N/A N/A
ENST00000535589 38.687±0.00 37.514±0.00 5.628±0.00 24.952±13.96 21.047±3.74 33.521±16.61 3.959±0.00 3.608±0.00 18.582±0.00 17.548±0.00 8.607±7.68 53.491±35.11 49.189±0.00 48.105±3.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002WV CIL_0002WV_0002 CGP 2:113889960-115845752

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 IEA Golgi membrane
GO:0002102 IEA podosome
GO:0005200 IDA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0005884 IEA actin filament
GO:0005885 IDA Arp2/3 protein complex
GO:0005911 IEA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0006928 TAS cellular component movement
GO:0007163 IEA establishment or maintenance of cell polarity
GO:0008356 IEA asymmetric cell division
GO:0009743 IEA response to carbohydrate
GO:0010592 IEA positive regulation of lamellipodium assembly
GO:0015629 TAS actin cytoskeleton
GO:0016020 IDA membrane
GO:0016344 IEA meiotic chromosome movement towards spindle pole
GO:0030027 IEA lamellipodium
GO:0030056 IEA hemidesmosome
GO:0030838 IEA positive regulation of actin filament polymerization
GO:0031252 IEA cell leading edge
GO:0033206 IEA meiotic cytokinesis
GO:0034314 IDA Arp2/3 complex-mediated actin nucleation
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043519 IEA regulation of myosin II filament organization
GO:0045087 TAS innate immune response
GO:0045666 IEA positive regulation of neuron differentiation
GO:0046677 IEA response to antibiotic
GO:0050775 IEA positive regulation of dendrite morphogenesis
GO:0051015 IDA actin filament binding
GO:0051321 IEA meiotic cell cycle
GO:0051491 IEA positive regulation of filopodium assembly
GO:0051653 IEA spindle localization
GO:0060076 IEA excitatory synapse
GO:0060271 IMP cilium morphogenesis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076772 ARP3 actin-related protein 3 homolog (yeast) protein_coding Danio_rerio
ENSDARG00000091138 ARP3 actin-related protein 3 homolog (yeast) protein_coding Danio_rerio
ENSMUSG00000026341 Actr3 ARP3 actin-related protein 3 protein_coding Mus_musculus

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