C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cell division cycle 73, Paf1/RNA polymerase II complex component
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026361 Cdc73 10090 - 1:143598800-143702893 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018337 Cdc73-001 143598800-143702893 protein_coding
  ENSMUST00000159794 Cdc73-003 143691315-143702200 nonsense_mediated_decay
  ENSMUST00000162638 Cdc73-002 143606161-143640581 processed_transcript
  ENSMUST00000188838 Cdc73-005 143633851-143636577 retained_intron
  ENSMUST00000189597 Cdc73-004 143639470-143642525 retained_intron

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018337ENSMUST00000162638
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018337 1.530±0.18 1.489±0.34 3.320±0.06 2.312±0.16 1.043±0.15 0.981±0.18 1.443±0.14 1.232±0.19 1.229±0.59 1.727±0.38 2.487±0.25 1.648±1.05 4.154±0.85 1.881±0.43
ENSMUST00000162638 N/A N/A 2.603±0.00 2.127±0.00 N/A 0.736±0.00 N/A N/A 1.707±0.96 N/A N/A 2.439±1.46 7.504±2.80 1.866±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005IF CIL_0005IF_0002 CGP 1:143598800-143702893

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000993 ISS RNA polymerase II core binding
GO:0001711 IMP endodermal cell fate commitment
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006378 ISS mRNA polyadenylation
GO:0007049 IEA cell cycle
GO:0008285 ISS negative regulation of cell proliferation
GO:0010390 IEA histone monoubiquitination
GO:0016055 IEA Wnt signaling pathway
GO:0016593 ISS Cdc73/Paf1 complex
GO:0019827 IMP stem cell maintenance
GO:0030177 ISS positive regulation of Wnt signaling pathway
GO:0031442 ISS positive regulation of mRNA 3'-end processing
GO:0031648 IEA protein destabilization
GO:0032968 ISS positive regulation of transcription elongation from RNA polymerase II promoter
GO:0033523 IEA histone H2B ubiquitination
GO:0045638 ISS negative regulation of myeloid cell differentiation
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048147 IEA negative regulation of fibroblast proliferation
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0071222 IDA cellular response to lipopolysaccharide
GO:2000134 ISS negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020201 cdc73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) protein_coding Danio_rerio
ENSG00000134371 CDC73 cell division cycle 73 protein_coding Homo_sapiens

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