C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate-ammonia ligase (glutamine synthetase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026473 Glul 10090 + 1:153899944-153909723 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086199 Glul-001 153899944-153909723 protein_coding
  ENSMUST00000139476 Glul-005 153900606-153907140 protein_coding
  ENSMUST00000140685 Glul-002 153901116-153906356 protein_coding
  ENSMUST00000153134 Glul-003 153903798-153907029 processed_transcript
  ENSMUST00000154576 Glul-004 153906043-153907116 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086199ENSMUST00000139476ENSMUST00000140685
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086199 375.571±87.00 330.587±47.24 98.036±12.17 61.640±25.35 539.331±131.41 179.906±27.23 92.872±17.54 343.117±30.33 275.161±213.99 129.711±28.07 85.607±32.68 169.441±39.61 49.997±29.61 98.015±8.62
ENSMUST00000139476 N/A N/A N/A 471.791±0.00 470.774±0.00 N/A N/A N/A N/A N/A N/A 211.679±0.00 70.562±5.96 361.281±0.00
ENSMUST00000140685 N/A N/A N/A N/A 618.216±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007Y8 CIL_0007Y8_0002 VISTA 1:153733856-154334857
CIL_00065F CIL_00065F_0002 CGP 1:153899944-154205689

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004351 IEA glutamate decarboxylase activity
GO:0004356 IEA glutamate-ammonia ligase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005791 IEA rough endoplasmic reticulum
GO:0006536 IEA glutamate metabolic process
GO:0008283 IEA cell proliferation
GO:0009267 IEP cellular response to starvation
GO:0009749 IMP response to glucose
GO:0016595 IEA glutamate binding
GO:0030145 IEA manganese ion binding
GO:0032024 IEA positive regulation of insulin secretion
GO:0042802 IEA identical protein binding
GO:0042995 IEA cell projection
GO:0043005 IEA neuron projection
GO:0043204 IEA perikaryon
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043234 IEA protein complex
GO:0043679 IEA axon terminus
GO:0044297 IDA cell body
GO:0045503 IEA dynein light chain binding
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0051260 IEA protein homooligomerization
GO:0051968 IEA positive regulation of synaptic transmission, glutamatergic
GO:0070062 IEA extracellular vesicular exosome
GO:0097386 IDA glial cell projection

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017339 glulb glutamate-ammonia ligase (glutamine synthase) b protein_coding Danio_rerio
ENSDARG00000069054 glula glutamate-ammonia ligase (glutamine synthase) a protein_coding Danio_rerio
ENSG00000135821 GLUL glutamate-ammonia ligase protein_coding Homo_sapiens

Loading