C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon regulatory factor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026638 Irf6 10090 + 1:193153112-193172042 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076521 Irf6-001 193153112-193172042 protein_coding
  ENSMUST00000138826 Irf6-004 193153112-193166868 retained_intron
  ENSMUST00000140066 Irf6-002 193156804-193164181 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076521ENSMUST00000138826
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076521 8.393±8.05 0.146±0.03 10.761±0.22 0.512±0.03 6.084±0.65 35.735±2.64 0.592±0.08 7.209±0.30 6.958±4.48 9.353±0.20 0.273±0.07 11.775±4.14 7.751±9.08 1.984±1.13
ENSMUST00000138826 N/A 0.202±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZL CIL_0007ZL_0002 VISTA 1:192841048-193441723
CIL_00089N CIL_00089N_0002 VISTA 1:193149329-193750185

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000975 IEA regulatory region DNA binding
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0007050 IEA cell cycle arrest
GO:0008285 IGI negative regulation of cell proliferation
GO:0030216 IMP keratinocyte differentiation
GO:0043588 IMP skin development
GO:0043616 IMP keratinocyte proliferation
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048468 IMP cell development
GO:0060644 IEP mammary gland epithelial cell differentiation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043296 irf6 interferon regulatory factor 6 protein_coding Danio_rerio
ENSG00000117595 IRF6 interferon regulatory factor 6 protein_coding Homo_sapiens

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