C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: low density lipoprotein receptor-related protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027070 Lrp2 10090 - 2:69424340-69586065 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000080953 Lrp2-001 69424340-69586065 protein_coding
  ENSMUST00000092551 Lrp2-003 69526366-69586029 protein_coding
  ENSMUST00000100051 Lrp2-002 69506204-69586029 protein_coding
  ENSMUST00000128742 Lrp2-004 69507623-69509145 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000080953ENSMUST00000100051
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000080953 1.632±1.56 0.050±0.01 0.057±0.04 0.223±0.13 0.022±0.01 0.042±0.01 0.176±0.02 115.025±28.34 0.026±0.02 6.059±1.40 0.003±0.00 1.688±0.61 10.045±12.65 0.318±0.17
ENSMUST00000100051 N/A N/A N/A N/A 0.028±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.970±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008HC CIL_0008HC_0002 VISTA 2:69119794-69721610
CIL_00063D CIL_00063D_0002 CGP 2:69380445-69586065
CIL_00063E CIL_00063E_0002 CGP 2:69424340-69667571

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 ISS receptor activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005765 IEA lysosomal membrane
GO:0005768 IDA endosome
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005903 IDA brush border
GO:0005905 IDA coated pit
GO:0006766 IMP vitamin metabolic process
GO:0006898 IMP receptor-mediated endocytosis
GO:0008283 IMP cell proliferation
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0017124 IEA SH3 domain binding
GO:0030139 IDA endocytic vesicle
GO:0030900 IMP forebrain development
GO:0031526 IDA brush border membrane
GO:0043235 ISO receptor complex
GO:0045177 IDA apical part of cell
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060649 lrp2a low density lipoprotein receptor-related protein 2a protein_coding Danio_rerio
ENSG00000081479 LRP2 low density lipoprotein receptor-related protein 2 protein_coding Homo_sapiens

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