C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glial cell line derived neurotrophic factor family receptor alpha 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027316 Gfra4 10090 - 2:131039632-131043088 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028787 Gfra4-004 131040176-131042682 protein_coding
  ENSMUST00000066958 Gfra4-002 131040208-131043088 protein_coding
  ENSMUST00000110234 Gfra4-006 131041232-131042682 protein_coding
  ENSMUST00000110235 Gfra4-003 131041232-131043088 protein_coding
  ENSMUST00000110239 Gfra4-005 131040208-131042682 protein_coding
  ENSMUST00000110240 Gfra4-001 131039632-131043088 protein_coding
  ENSMUST00000136569 Gfra4-007 131039640-131041511 retained_intron
  ENSMUST00000156509 Gfra4-008 131039639-131041457 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028787ENSMUST00000110234ENSMUST00000110235ENSMUST00000110239ENSMUST00000136569ENSMUST00000156509
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028787 N/A 1.538±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000110234 N/A 4.273±2.04 N/A N/A N/A 2.804±0.94 N/A N/A N/A N/A N/A 6.205±0.54 N/A N/A
ENSMUST00000110235 N/A 7.873±0.23 N/A N/A 4.357±0.00 2.879±0.58 N/A N/A N/A N/A N/A 8.699±0.00 N/A N/A
ENSMUST00000110239 N/A N/A N/A N/A N/A N/A N/A N/A 0.022±0.00 N/A N/A N/A N/A N/A
ENSMUST00000136569 2.801±1.77 2.910±0.66 17.719±3.55 7.808±1.88 2.037±0.39 2.674±0.62 2.129±0.41 0.819±0.24 0.106±0.05 0.830±0.02 0.245±0.08 3.683±1.62 0.534±0.33 2.122±1.18
ENSMUST00000156509 6.475±3.21 6.735±1.57 43.991±1.22 13.862±6.89 5.246±0.88 7.186±1.29 5.158±0.69 1.922±0.53 0.149±0.10 1.831±0.31 0.504±0.20 8.602±4.23 1.286±0.59 21.761±9.97

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00067S CIL_00067S_0003 CGP 2:130906495-131043088
CIL_0003DE CIL_0003DE_0002 CGP 2:131039632-131063814

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0007169 TAS transmembrane receptor protein tyrosine kinase signaling pathway
GO:0015026 TAS coreceptor activity
GO:0016167 IEA glial cell-derived neurotrophic factor receptor activity
GO:0030279 IMP negative regulation of ossification
GO:0031225 IEA anchored component of membrane
GO:0035860 IEA glial cell-derived neurotrophic factor receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056651 gfra4 GDNF family receptor alpha 4 protein_coding Danio_rerio
ENSDARG00000074582 BX247898.1 Uncharacterized protein protein_coding Danio_rerio
ENSG00000125861 GFRA4 GDNF family receptor alpha 4 protein_coding Homo_sapiens

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