C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: E2F transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027490 E2f1 10090 - 2:154559407-154569892 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000894 E2f1-002 154559634-154569720 protein_coding
  ENSMUST00000103145 E2f1-001 154559407-154569892 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000894ENSMUST00000103145
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000894 3.346±2.07 2.470±0.49 1.657±0.02 2.847±0.96 1.499±0.35 N/A 0.264±0.04 0.606±0.30 2.856±1.97 3.475±0.79 N/A 2.415±1.02 4.005±2.05 0.727±0.30
ENSMUST00000103145 2.853±1.17 3.586±0.15 1.015±0.14 2.986±1.57 1.960±0.59 4.921±0.48 0.220±0.08 0.657±0.36 9.960±11.34 1.996±0.28 0.192±0.09 12.383±4.43 2.160±1.23 1.442±0.70

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00003O CIL_00003O_0002 CGP 2:154551776-154569892
CIL_0001NZ CIL_0001NZ_0002 CGP 2:154559407-154603708

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000077 ISS DNA damage checkpoint
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001047 IEA core promoter binding
GO:0003677 ISO DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007283 IEA spermatogenesis
GO:0008134 IPI transcription factor binding
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010628 IEA positive regulation of gene expression
GO:0030900 IMP forebrain development
GO:0035189 IEA Rb-E2F complex
GO:0043276 IDA anoikis
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0048255 IEA mRNA stabilization
GO:0051726 IDA regulation of cell cycle
GO:0071398 IEA cellular response to fatty acid
GO:0071456 IEA cellular response to hypoxia
GO:0071930 IEA negative regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0072332 IDA intrinsic apoptotic signaling pathway by p53 class mediator
GO:1990086 IDA lens fiber cell apoptotic process
GO:2000045 IEA regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079349 E2F1 E2F transcription factor 1 protein_coding Danio_rerio
ENSG00000101412 E2F1 E2F transcription factor 1 protein_coding Homo_sapiens

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