C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein), beta 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027669 Gnb4 10090 - 3:32580332-32616585 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000108234 Gnb4-002 32583998-32616517 protein_coding
  ENSMUST00000143588 Gnb4-006 32599844-32616529 retained_intron
  ENSMUST00000144292 Gnb4-004 32592211-32616525 retained_intron
  ENSMUST00000152901 Gnb4-003 32583998-32616525 retained_intron
  ENSMUST00000155737 Gnb4-001 32580332-32616585 protein_coding
  ENSMUST00000184130 Gnb4-005 32585055-32616522 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000108234ENSMUST00000144292ENSMUST00000152901ENSMUST00000155737ENSMUST00000184130
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000108234 3.945±0.00 4.566±2.78 4.705±0.38 4.408±0.10 3.757±2.14 1.199±0.00 1.549±0.00 1.299±0.00 1.171±0.34 5.568±0.00 0.949±0.14 3.057±0.83 15.045±8.34 0.333±0.05
ENSMUST00000144292 N/A N/A N/A N/A 1.731±0.00 N/A N/A N/A N/A N/A 0.213±0.00 1.708±0.92 2.570±0.00 0.077±0.00
ENSMUST00000152901 4.746±0.86 3.062±0.74 3.959±0.56 4.678±0.00 4.367±1.41 2.993±1.03 1.959±0.24 1.199±0.28 0.825±0.51 8.649±1.54 1.074±0.26 6.876±1.63 15.532±4.49 0.338±0.09
ENSMUST00000155737 2.687±0.94 1.620±0.54 2.974±0.09 4.506±2.51 2.143±0.35 1.398±0.17 1.368±0.26 1.195±0.19 0.457±0.20 4.213±0.53 0.549±0.26 3.511±1.05 4.095±2.22 0.148±0.06
ENSMUST00000184130 11.237±2.03 4.340±0.43 N/A 4.838±0.90 11.598±8.97 3.490±0.72 3.916±0.43 1.847±0.25 0.943±0.69 7.067±2.03 N/A 9.615±3.27 N/A 0.488±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001FF CIL_0001FF_0002 CGP 3:32529465-32616585
CIL_0001FG CIL_0001FG_0002 CGP 3:32580332-32726968

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 ISA GTPase activity
GO:0004871 IEA signal transducer activity
GO:0005765 IEA lysosomal membrane
GO:0005834 ISA heterotrimeric G-protein complex
GO:0006184 ISA GTP catabolic process
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0021762 IEA substantia nigra development
GO:0032403 ISO protein complex binding
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019278 CABZ01087197.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000034480 gnb4b guanine nucleotide binding protein (G protein), beta polypeptide 4b protein_coding Danio_rerio
ENSG00000114450 GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 protein_coding Homo_sapiens

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