C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pentraxin related gene
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027832 Ptx3 10090 + 3:66219910-66225805 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029421 Ptx3-001 66219910-66225805 protein_coding
  ENSMUST00000182521 Ptx3-002 66220245-66221430 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029421ENSMUST00000182521
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029421 1.172±0.04 0.277±0.06 0.389±0.13 4.741±4.11 3.166±2.23 0.173±0.07 0.321±0.10 0.364±0.20 0.065±0.05 0.370±0.21 2.092±0.87 1.828±0.73 0.207±0.24 0.166±0.08
ENSMUST00000182521 0.676±0.27 0.458±0.22 0.138±0.00 0.101±0.00 4.873±1.12 0.308±0.16 0.117±0.03 0.140±0.09 0.035±0.02 0.356±0.00 3.196±0.64 1.037±0.63 0.099±0.06 0.031±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00081H CIL_00081H_0002 VISTA 3:65626895-66230134
CIL_00028W CIL_00028W_0002 CGP 3:65946151-66296837
CIL_0004JX CIL_0004JX_0003 CGP 3:66053558-66296837

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001849 IEA complement component C1q binding
GO:0001872 IMP (1->3)-beta-D-glucan binding
GO:0001878 IMP response to yeast
GO:0005615 IEA extracellular space
GO:0008228 IMP opsonization
GO:0044869 IEA negative regulation by host of viral exo-alpha-sialidase activity
GO:0044871 IEA negative regulation by host of viral glycoprotein metabolic process
GO:0045087 IEA innate immune response
GO:0045429 IMP positive regulation of nitric oxide biosynthetic process
GO:0046597 IEA negative regulation of viral entry into host cell
GO:0046790 IEA virion binding
GO:0050766 IMP positive regulation of phagocytosis
GO:1903016 IEA negative regulation of exo-alpha-sialidase activity
GO:1903019 IEA negative regulation of glycoprotein metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068275 ptx3a pentraxin 3, long a protein_coding Danio_rerio
ENSDARG00000079515 ptx3b pentraxin 3, long b protein_coding Danio_rerio
ENSG00000163661 PTX3 pentraxin 3, long protein_coding Homo_sapiens

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