C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adenosine deaminase, RNA-specific
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000121094 Adar-003 ENSMUSG00000027951 10090 + 3:89730748-89751406 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; LiverENSMUST00000121094
Transcript ID Liver
ENSMUST00000121094 2.948±1.04

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001649 IMP osteoblast differentiation
GO:0001701 IMP in utero embryonic development
GO:0002244 IMP hematopoietic progenitor cell differentiation
GO:0002566 IDA somatic diversification of immune receptors via somatic mutation
GO:0003692 TAS left-handed Z-DNA binding
GO:0003726 IDA double-stranded RNA adenosine deaminase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006382 IMP adenosine to inosine editing
GO:0006397 IEA mRNA processing
GO:0009615 ISS response to virus
GO:0030218 IMP erythrocyte differentiation
GO:0035196 IMP production of miRNAs involved in gene silencing by miRNA
GO:0035280 ISO miRNA loading onto RISC involved in gene silencing by miRNA
GO:0035455 ISS response to interferon-alpha
GO:0043066 IMP negative regulation of apoptotic process
GO:0044387 IMP negative regulation of protein kinase activity by regulation of protein phosphorylation
GO:0044530 ISS supraspliceosomal complex
GO:0045070 IMP positive regulation of viral genome replication
GO:0045071 IMP negative regulation of viral genome replication
GO:0045087 IEA innate immune response
GO:0046872 IEA metal ion binding
GO:0051607 IMP defense response to virus
GO:0060216 IMP definitive hemopoiesis
GO:0060339 IMP negative regulation of type I interferon-mediated signaling pathway
GO:0061484 IMP hematopoietic stem cell homeostasis
GO:1900369 IMP negative regulation of RNA interference

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000368471 ADAR-002 protein_coding Homo_sapiens 0 1341
ENST00000368474 ADAR-001 protein_coding Homo_sapiens 0 1341
ENST00000492630 ADAR-004 retained_intron Homo_sapiens 0 398
ENST00000529168 ADAR-007 protein_coding Homo_sapiens 0 2115
ENST00000530954 ADAR-010 retained_intron Homo_sapiens 0 551
ENST00000534279 ADAR-009 retained_intron Homo_sapiens 0 381

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