C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 7, subfamily a, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028240 Cyp7a1 10090 - 4:6265612-6275633 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029905 Cyp7a1-001 6265612-6275631 protein_coding
  ENSMUST00000147346 Cyp7a1-002 6272805-6275633 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastLiverMuscleOvaryTestisENSMUST00000029905
Transcript ID Adipose Breast Liver Muscle Ovary Testis
ENSMUST00000029905 0.032±0.00 0.029±0.00 6.505±6.91 0.009±0.00 0.073±0.03 0.041±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002RI CIL_0002RI_0002 CGP 4:6191098-6275633
CIL_0001T7 CIL_0001T7_0002 CGP 4:6265612-6408423

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005783 IEA endoplasmic reticulum
GO:0006699 ISS bile acid biosynthetic process
GO:0006707 ISS cholesterol catabolic process
GO:0008123 ISS cholesterol 7-alpha-monooxygenase activity
GO:0016020 IEA membrane
GO:0020037 IEA heme binding
GO:0042632 ISS cholesterol homeostasis
GO:0043231 ISS intracellular membrane-bounded organelle
GO:0055114 IEA oxidation-reduction process
GO:0070857 ISS regulation of bile acid biosynthetic process
GO:0070859 TAS positive regulation of bile acid biosynthetic process
GO:0071333 ISS cellular response to glucose stimulus
GO:0071397 ISS cellular response to cholesterol

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069018 cyp7a1a cytochrome P450, family 7, subfamily A, polypeptide 1a protein_coding Danio_rerio
ENSG00000167910 CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1 protein_coding Homo_sapiens

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