C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 7, subfamily A, polypeptide 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167910 CYP7A1 9606 - 8:58490178-58500236 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301645 CYP7A1-001 58490178-58500236 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartKidneyLiverLungOvaryPlacentaTestisENST00000301645
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000301645 0.003±0.00 0.037±0.00 0.018±0.00 0.003±0.00 0.035±0.01 0.016±0.00 5.457±5.45 0.027±0.01 0.043±0.00 0.027±0.00 0.031±0.02 0.066±0.03

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008CM CIL_0008CM_0001 VISTA 8:57955651-58557562
CIL_0002RI CIL_0002RI_0001 CGP 8:58411264-58500236
CIL_0001T7 CIL_0001T7_0001 CGP 8:58490178-58582860

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006699 ISS bile acid biosynthetic process
GO:0006707 ISS cholesterol catabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008123 ISS cholesterol 7-alpha-monooxygenase activity
GO:0008206 TAS bile acid metabolic process
GO:0016125 TAS sterol metabolic process
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IEA heme binding
GO:0042632 ISS cholesterol homeostasis
GO:0043231 ISS intracellular membrane-bounded organelle
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070857 ISS regulation of bile acid biosynthetic process
GO:0071333 IDA cellular response to glucose stimulus
GO:0071397 ISS cellular response to cholesterol

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000069018 cyp7a1a cytochrome P450, family 7, subfamily A, polypeptide 1a protein_coding Danio_rerio
ENSMUSG00000028240 Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 protein_coding Mus_musculus

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