C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Eph receptor A7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028289 Epha7 10090 + 4:28813131-28967499 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000029964 Epha7-001 28813131-28967499 protein_coding
  ENSMUST00000080934 Epha7-002 28813131-28947047 protein_coding
  ENSMUST00000108191 Epha7-004 28813250-28967499 protein_coding
  ENSMUST00000108194 Epha7-003 28813152-28966815 protein_coding
  ENSMUST00000129029 Epha7-007 28871841-28943500 processed_transcript
  ENSMUST00000129912 Epha7-008 28871924-28946334 processed_transcript
  ENSMUST00000136827 Epha7-006 28815429-28821199 processed_transcript
  ENSMUST00000149030 Epha7-005 28813326-28873801 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000029964ENSMUST00000080934ENSMUST00000108191ENSMUST00000108194ENSMUST00000129029ENSMUST00000129912ENSMUST00000136827ENSMUST00000149030
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000029964 0.321±0.05 N/A 1.265±0.06 4.377±1.74 N/A 0.470±0.00 0.350±0.10 0.121±0.03 0.229±0.15 0.546±0.06 0.131±0.02 0.337±0.00 0.321±0.18 0.502±0.03
ENSMUST00000080934 N/A N/A N/A 3.918±0.74 0.124±0.00 0.268±0.00 N/A 0.086±0.00 0.162±0.00 N/A 0.064±0.00 N/A N/A N/A
ENSMUST00000108191 0.027±0.00 0.085±0.04 N/A 1.353±0.01 0.114±0.06 0.712±0.25 0.213±0.03 0.157±0.07 0.122±0.02 0.433±0.16 0.036±0.00 0.208±0.09 0.172±0.06 N/A
ENSMUST00000108194 0.063±0.00 0.209±0.14 N/A 6.729±0.00 0.295±0.18 0.415±0.01 N/A N/A 0.134±0.10 N/A 0.083±0.03 0.220±0.14 N/A N/A
ENSMUST00000129029 0.368±0.35 0.445±0.00 N/A N/A N/A 1.039±0.00 N/A 0.367±0.00 N/A N/A N/A 0.131±0.00 N/A N/A
ENSMUST00000129912 N/A N/A N/A N/A N/A N/A N/A N/A 0.159±0.02 N/A N/A 0.271±0.00 N/A N/A
ENSMUST00000136827 N/A 0.083±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.212±0.00 N/A N/A
ENSMUST00000149030 N/A 0.316±0.02 N/A N/A 0.056±0.02 N/A N/A N/A 0.042±0.00 N/A N/A 0.160±0.04 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008LE CIL_0008LE_0002 VISTA 4:28562692-29163921

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005003 IEA ephrin receptor activity
GO:0005004 IDA GPI-linked ephrin receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 IC integral component of plasma membrane
GO:0007420 IMP brain development
GO:0008046 IMP axon guidance receptor activity
GO:0016310 ISS phosphorylation
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0022407 IDA regulation of cell-cell adhesion
GO:0030425 IEA dendrite
GO:0031290 IMP retinal ganglion cell axon guidance
GO:0031594 IEA neuromuscular junction
GO:0031952 IDA regulation of protein autophosphorylation
GO:0043025 IEA neuronal cell body
GO:0043065 IEA positive regulation of apoptotic process
GO:0043281 IDA regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043525 IMP positive regulation of neuron apoptotic process
GO:0045211 IEA postsynaptic membrane
GO:0045499 IDA chemorepellent activity
GO:0046875 IEA ephrin receptor binding
GO:0048013 IDA ephrin receptor signaling pathway
GO:0048755 IMP branching morphogenesis of a nerve
GO:0050730 IDA regulation of peptidyl-tyrosine phosphorylation
GO:0050919 IDA negative chemotaxis
GO:0070372 ISS regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004635 epha7 eph receptor A7 protein_coding Danio_rerio
ENSG00000135333 EPHA7 EPH receptor A7 protein_coding Homo_sapiens

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