C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028551 Cdkn2c 10090 - 4:109660876-109667189 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000063531 Cdkn2c-002 109660876-109665372 protein_coding
  ENSMUST00000097921 Cdkn2c-001 109660876-109667189 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000063531ENSMUST00000097921
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000063531 31.783±16.56 N/A 5.408±0.40 0.447±0.10 22.469±9.97 N/A 2.415±0.30 5.154±0.76 1.248±0.44 5.224±1.97 4.630±0.52 16.915±9.03 1.005±0.69 N/A
ENSMUST00000097921 17.437±8.38 9.271±3.17 2.373±0.41 2.375±1.93 9.967±2.73 4.089±1.11 1.497±0.30 1.621±0.28 5.857±5.66 2.611±0.42 1.894±0.23 5.984±1.89 2.455±1.48 32.762±3.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AC CIL_0009AC_0002 VISTA 4:109462244-110063771
CIL_0008US CIL_0008US_0002 VISTA 4:109505979-110107022
CIL_0008UT CIL_0008UT_0002 VISTA 4:109558711-110160443
CIL_0008K0 CIL_0008K0_0002 VISTA 4:109582013-110183287

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 IEA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0004861 IEA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007050 IEA cell cycle arrest
GO:0008285 IGI negative regulation of cell proliferation
GO:0019901 IEA protein kinase binding
GO:0030308 IEA negative regulation of cell growth
GO:0042326 IEA negative regulation of phosphorylation
GO:0048709 IEA oligodendrocyte differentiation
GO:0071901 IEA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057610 cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) protein_coding Danio_rerio
ENSG00000123080 CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) protein_coding Homo_sapiens

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