C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000123080 CDKN2C 9606 + 1:50960745-50974633 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262662 CDKN2C-001 50960745-50974633 protein_coding
  ENST00000371761 CDKN2C-002 50969944-50974558 protein_coding
  ENST00000396148 CDKN2C-201 50968695-50974633 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262662ENST00000371761ENST00000396148
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262662 N/A N/A N/A N/A N/A N/A N/A 0.432±0.00 0.227±0.00 N/A 0.327±0.00 0.223±0.00 N/A 0.642±0.00
ENST00000371761 3.579±0.00 2.000±0.00 0.224±0.00 0.746±0.37 8.834±5.79 4.835±3.06 1.349±0.48 1.371±0.30 2.815±1.72 2.110±1.46 1.574±0.13 2.237±1.32 2.595±0.00 2.482±1.03
ENST00000396148 5.519±0.00 3.171±0.00 0.471±0.00 3.156±2.52 15.990±15.50 4.508±3.33 2.676±2.56 2.600±0.00 1.232±0.26 2.897±2.45 0.371±0.00 5.688±4.37 4.681±0.25 5.109±3.52

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009AC CIL_0009AC_0001 VISTA 1:50399523-51001114
CIL_0006WA CIL_0006WA_0002 CGP 1:50439478-50974633

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000079 IDA regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 IDA G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0004861 IDA cyclin-dependent protein serine/threonine kinase inhibitor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0007050 IDA cell cycle arrest
GO:0008285 IDA negative regulation of cell proliferation
GO:0019901 IPI protein kinase binding
GO:0030308 IDA negative regulation of cell growth
GO:0042326 IDA negative regulation of phosphorylation
GO:0048709 IEA oligodendrocyte differentiation
GO:0071901 IDA negative regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000057610 cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) protein_coding Danio_rerio
ENSMUSG00000028551 Cdkn2c cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) protein_coding Mus_musculus

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