C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T cell acute lymphocytic leukemia 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028717 Tal1 10090 + 4:115056426-115071755 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030489 Tal1-001 115056426-115071755 protein_coding
  ENSMUST00000136946 Tal1-002 115057438-115063570 protein_coding
  ENSMUST00000161601 Tal1-003 115057811-115071228 protein_coding
  ENSMUST00000162489 Tal1-004 115059508-115070469 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000030489ENSMUST00000136946ENSMUST00000161601ENSMUST00000162489
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000030489 N/A 0.317±0.12 0.473±0.00 3.806±2.34 0.711±0.35 0.219±0.20 N/A 0.167±0.00 38.584±23.16 0.795±0.00 N/A 0.554±0.21 1.980±1.18
ENSMUST00000136946 N/A 1.613±0.89 N/A N/A 1.265±0.00 0.411±0.18 N/A N/A N/A N/A N/A 1.865±0.47 N/A
ENSMUST00000161601 0.220±0.00 0.500±0.00 0.241±0.00 1.502±0.00 0.282±0.00 N/A 0.284±0.00 0.122±0.00 0.031±0.00 N/A 0.112±0.00 0.374±0.09 0.670±0.00
ENSMUST00000162489 0.438±0.06 0.812±0.33 0.331±0.00 2.945±0.00 0.783±0.23 0.321±0.07 0.331±0.09 0.225±0.13 20.695±16.17 1.895±0.89 0.119±0.00 0.899±0.45 0.889±0.48

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IEA histone deacetylase complex
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0000980 IDA RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001085 IEA RNA polymerase II transcription factor binding
GO:0001525 IMP angiogenesis
GO:0003677 IDA DNA binding
GO:0003682 ISO chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007626 IMP locomotory behavior
GO:0019899 IEA enzyme binding
GO:0021527 IGI spinal cord association neuron differentiation
GO:0030097 IDA hemopoiesis
GO:0030099 IMP myeloid cell differentiation
GO:0030182 IMP neuron differentiation
GO:0030218 IDA erythrocyte differentiation
GO:0030219 IMP megakaryocyte differentiation
GO:0030220 IMP platelet formation
GO:0030221 IEA basophil differentiation
GO:0031334 IEA positive regulation of protein complex assembly
GO:0033193 IEA Lsd1/2 complex
GO:0035162 IMP embryonic hemopoiesis
GO:0035855 IMP megakaryocyte development
GO:0042127 IMP regulation of cell proliferation
GO:0042826 IEA histone deacetylase binding
GO:0043234 IPI protein complex
GO:0043249 IMP erythrocyte maturation
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045165 IMP cell fate commitment
GO:0045637 IMP regulation of myeloid cell differentiation
GO:0045648 IDA positive regulation of erythrocyte differentiation
GO:0045799 IEA positive regulation of chromatin assembly or disassembly
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0048699 IMP generation of neurons
GO:0051781 IEA positive regulation of cell division
GO:0060018 IMP astrocyte fate commitment
GO:0060216 IMP definitive hemopoiesis
GO:0060217 IMP hemangioblast cell differentiation
GO:0060218 IMP hematopoietic stem cell differentiation
GO:0060375 IMP regulation of mast cell differentiation
GO:0070888 IDA E-box binding
GO:2000036 IMP regulation of stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019930 tal1 T-cell acute lymphocytic leukemia 1 protein_coding Danio_rerio
ENSG00000162367 TAL1 T-cell acute lymphocytic leukemia 1 protein_coding Homo_sapiens

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