C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: T-cell acute lymphocytic leukemia 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000019930 tal1 7955 + 22:16757547-16767302 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000083063 tal1-001 16757547-16767302 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000083063
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000083063 18.375±12.29 7.771±2.96 8.019±2.63 0.201±0.00 1.499±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001568 IMP blood vessel development
GO:0001570 IDA vasculogenesis
GO:0003007 IGI heart morphogenesis
GO:0003677 IMP DNA binding
GO:0005634 IC nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-dependent
GO:0007275 IEA multicellular organismal development
GO:0007507 IGI heart development
GO:0030097 IDA hemopoiesis
GO:0030099 IEP myeloid cell differentiation
GO:0030154 IEA cell differentiation
GO:0030218 IGI erythrocyte differentiation
GO:0030878 IMP thyroid gland development
GO:0035050 IMP embryonic heart tube development
GO:0035162 IMP embryonic hemopoiesis
GO:0045603 IMP positive regulation of endothelial cell differentiation
GO:0046983 IEA protein dimerization activity
GO:0048368 IMP lateral mesoderm development
GO:0048823 IMP nucleate erythrocyte development
GO:0048844 IMP artery morphogenesis
GO:0060214 IMP endocardium formation
GO:0060215 IDA primitive hemopoiesis
GO:0060216 IMP definitive hemopoiesis
GO:0060217 IMP hemangioblast cell differentiation
GO:0060218 IMP hematopoietic stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000104903 LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 protein_coding Homo_sapiens
ENSG00000162367 TAL1 T-cell acute lymphocytic leukemia 1 protein_coding Homo_sapiens
ENSMUSG00000028717 Tal1 T cell acute lymphocytic leukemia 1 protein_coding Mus_musculus
ENSMUSG00000034041 Lyl1 lymphoblastomic leukemia 1 protein_coding Mus_musculus

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