C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hepatocyte growth factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028864 Hgf 10090 + 5:16553550-16619439 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030683 Hgf-201 16553550-16619439 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030683
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030683 0.251±0.05 0.432±0.00 0.056±0.00 0.873±0.69 0.447±0.17 0.147±0.04 0.235±0.09 0.887±0.82 1.361±0.76 0.022±0.01 0.872±0.28 0.259±0.07 0.259±0.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CV CIL_0003CV_0002 CGP 5:15934691-16619439

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IDA activation of MAPK activity
GO:0000902 IDA cell morphogenesis
GO:0001889 IDA liver development
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 IEA extracellular space
GO:0006508 IEA proteolysis
GO:0008083 IEA growth factor activity
GO:0008283 IDA cell proliferation
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 IEA membrane
GO:0030212 IEA hyaluronan metabolic process
GO:0030335 IEA positive regulation of cell migration
GO:0031100 IEA organ regeneration
GO:0031643 IEA positive regulation of myelination
GO:0035729 IEA cellular response to hepatocyte growth factor stimulus
GO:0042056 IEA chemoattractant activity
GO:0042802 IEA identical protein binding
GO:0043066 IEA negative regulation of apoptotic process
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045766 IEA positive regulation of angiogenesis
GO:0046982 IEA protein heterodimerization activity
GO:0048012 IDA hepatocyte growth factor receptor signaling pathway
GO:0050731 IEA positive regulation of peptidyl-tyrosine phosphorylation
GO:0050918 IEA positive chemotaxis
GO:0051450 IDA myoblast proliferation
GO:0060326 IEA cell chemotaxis
GO:0060665 IMP regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0070572 IEA positive regulation of neuron projection regeneration
GO:0090201 IEA negative regulation of release of cytochrome c from mitochondria
GO:1901299 IEA negative regulation of hydrogen peroxide-mediated programmed cell death
GO:1902042 IDA negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000573 IEA positive regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045544 hgfa hepatocyte growth factor a protein_coding Danio_rerio
ENSDARG00000063316 HGF (2 of 2) hepatocyte growth factor (hepapoietin A; scatter factor) protein_coding Danio_rerio
ENSG00000019991 HGF hepatocyte growth factor (hepapoietin A; scatter factor) protein_coding Homo_sapiens

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