C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DNA fragmentation factor, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028974 Dffa 10090 + 4:149104146-149120647 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030816 Dffa-001 149104146-149120647 protein_coding
  ENSMUST00000103216 Dffa-002 149104146-149118870 protein_coding
  ENSMUST00000153781 Dffa-003 149107769-149108234 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030816ENSMUST00000103216
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030816 5.113±1.47 3.886±1.39 7.511±0.75 6.463±1.96 7.681±3.04 6.728±1.66 4.899±2.69 4.666±1.16 5.825±1.80 4.354±1.12 8.266±1.08 4.394±1.29 10.380±2.94 1.508±0.45
ENSMUST00000103216 3.092±0.21 2.695±0.82 3.455±0.00 4.615±0.00 3.738±0.98 3.029±0.26 4.825±0.20 3.249±0.52 2.750±0.81 3.402±0.31 4.531±0.92 2.876±0.72 5.699±2.13 1.393±0.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RU CIL_0008RU_0002 VISTA 4:148508781-149109416
CIL_0008S2 CIL_0008S2_0002 VISTA 4:148555953-149160332
CIL_00082Y CIL_00082Y_0002 VISTA 4:148576108-149176659
CIL_00085P CIL_00085P_0002 VISTA 4:148597228-149198219
CIL_0007WE CIL_0007WE_0002 VISTA 4:148621504-149222572
CIL_0008IM CIL_0008IM_0002 VISTA 4:148744049-149345133

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IBA nuclear chromatin
GO:0005515 IPI protein binding
GO:0005634 ISO nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IEA cytosol
GO:0043065 IMP positive regulation of apoptotic process
GO:0070242 IMP thymocyte apoptotic process
GO:1900118 IBA negative regulation of execution phase of apoptosis
GO:1902511 IMP negative regulation of apoptotic DNA fragmentation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055770 dffa DNA fragmentation factor, alpha polypeptide protein_coding Danio_rerio
ENSG00000160049 DFFA DNA fragmentation factor, 45kDa, alpha polypeptide protein_coding Homo_sapiens

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