C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 2B, subunit 4 delta
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029145 Eif2b4 10090 - 5:31187558-31193430 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000077693 Eif2b4-001 31187558-31193430 protein_coding
  ENSMUST00000114603 Eif2b4-002 31187568-31193014 protein_coding
  ENSMUST00000114605 Eif2b4-003 31187567-31193008 protein_coding
  ENSMUST00000128037 Eif2b4-006 31189589-31191151 protein_coding
  ENSMUST00000130667 Eif2b4-008 31191200-31193139 processed_transcript
  ENSMUST00000134888 Eif2b4-004 31191718-31193418 processed_transcript
  ENSMUST00000139216 Eif2b4-005 31191330-31192999 processed_transcript
  ENSMUST00000153986 Eif2b4-007 31189402-31190861 retained_intron
  ENSMUST00000166769 Eif2b4-201 31187559-31193139 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000077693ENSMUST00000114603ENSMUST00000114605ENSMUST00000153986ENSMUST00000166769
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000077693 N/A N/A 10.969±1.52 N/A N/A N/A N/A 11.157±3.40 N/A 7.051±1.75 7.969±0.00 13.967±3.54 6.891±0.00
ENSMUST00000114603 N/A 10.880±0.50 N/A N/A N/A N/A N/A 7.068±1.96 N/A 7.379±1.95 N/A N/A N/A
ENSMUST00000114605 17.258±2.33 N/A N/A 22.324±2.99 14.721±2.43 18.006±4.14 19.361±1.47 15.974±4.30 15.817±0.00 5.322±0.00 24.334±5.14 23.018±4.37 33.245±1.78
ENSMUST00000153986 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 32.277±0.00
ENSMUST00000166769 N/A N/A N/A 12.167±0.97 7.332±0.00 N/A N/A 4.774±0.00 N/A 6.577±0.91 N/A N/A 11.349±0.80

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001DH CIL_0001DH_0002 CGP 5:31156005-31193430
CIL_000133 CIL_000133_0002 CGP 5:31187558-31198900

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001541 ISS ovarian follicle development
GO:0003743 ISS translation initiation factor activity
GO:0005085 IBA guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005851 ISS eukaryotic translation initiation factor 2B complex
GO:0006413 ISS translational initiation
GO:0006446 IBA regulation of translational initiation
GO:0014003 ISS oligodendrocyte development
GO:0042552 ISS myelination
GO:0043547 ISS positive regulation of GTPase activity
GO:0044237 IEA cellular metabolic process
GO:0045947 IBA negative regulation of translational initiation
GO:0051716 ISS cellular response to stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014004 eif2b4 eukaryotic translation initiation factor 2B, subunit 4 delta protein_coding Danio_rerio
ENSG00000115211 EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa protein_coding Homo_sapiens

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