C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kelch-like 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029312 Klhl8 10090 - 5:103861973-103911259 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031254 Klhl8-001 103862050-103911259 protein_coding
  ENSMUST00000112811 Klhl8-002 103861973-103886290 protein_coding
  ENSMUST00000112815 Klhl8-004 103861973-103886290 protein_coding
  ENSMUST00000131843 Klhl8-003 103862080-103886290 nonsense_mediated_decay
  ENSMUST00000147184 Klhl8-005 103870310-103874369 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031254ENSMUST00000112815ENSMUST00000131843ENSMUST00000147184
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031254 6.131±1.50 3.645±0.65 3.821±0.22 11.079±2.92 3.997±1.29 1.663±0.55 4.974±0.77 3.293±0.43 0.903±0.16 4.465±1.19 7.742±1.82 7.707±2.70 1.634±0.16 7.300±2.76
ENSMUST00000112815 N/A N/A N/A N/A N/A 0.293±0.00 N/A N/A N/A N/A N/A 2.033±0.34 N/A 0.579±0.00
ENSMUST00000131843 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.149±0.00
ENSMUST00000147184 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.196±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000BR CIL_0000BR_0002 CGP 5:103692374-103911259
CIL_0000BS CIL_0000BS_0002 CGP 5:103861973-103977410

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005634 IEA nucleus
GO:0016567 ISS protein ubiquitination
GO:0031463 ISS Cul3-RING ubiquitin ligase complex
GO:0042787 ISS protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015344 klhl8 kelch-like 8 (Drosophila) protein_coding Danio_rerio
ENSG00000145332 KLHL8 kelch-like family member 8 protein_coding Homo_sapiens

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