C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: kelch-like family member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000145332 KLHL8 9606 - 4:87160103-87240314 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000273963 KLHL8-001 87160103-87220608 protein_coding
  ENST00000425278 KLHL8-003 87161043-87220525 protein_coding
  ENST00000498875 KLHL8-002 87160249-87220536 protein_coding
  ENST00000504029 KLHL8-006 87170199-87220545 processed_transcript
  ENST00000505388 KLHL8-007 87163883-87220497 processed_transcript
  ENST00000506274 KLHL8-008 87219524-87240314 processed_transcript
  ENST00000506985 KLHL8-004 87162444-87220463 nonsense_mediated_decay
  ENST00000512111 KLHL8-005 87162522-87220268 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000273963ENST00000425278ENST00000498875ENST00000504029ENST00000506985ENST00000512111
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000273963 1.748±0.00 N/A N/A 1.508±0.00 0.561±0.05 1.894±0.04 1.254±0.00 1.308±0.00 0.401±0.00 0.767±0.00 4.563±0.00 1.128±0.37 0.835±0.16 1.452±0.59
ENST00000425278 1.523±0.00 1.054±0.00 0.865±0.00 1.446±0.81 1.510±0.82 0.878±0.00 0.881±0.17 1.263±0.00 1.119±0.85 2.257±1.32 1.299±0.15 1.073±0.55 0.633±0.38 1.389±0.49
ENST00000498875 N/A 0.526±0.00 0.777±0.00 0.955±0.01 0.907±0.16 0.695±0.27 0.284±0.00 2.111±0.28 0.559±0.00 0.690±0.06 1.186±0.00 0.314±0.00 0.312±0.00 1.533±0.00
ENST00000504029 N/A N/A N/A N/A N/A 6.040±0.00 N/A N/A N/A N/A 2.396±0.00 4.148±1.68 2.029±0.00 3.818±0.00
ENST00000506985 N/A N/A N/A 3.151±0.00 1.113±0.00 1.816±0.00 0.631±0.00 2.586±0.00 2.462±0.00 N/A N/A N/A N/A N/A
ENST00000512111 N/A N/A 1.071±0.00 N/A N/A N/A 1.035±0.00 N/A 2.058±0.00 1.314±0.00 0.651±0.00 1.590±0.00 N/A 0.854±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000BR CIL_0000BR_0001 CGP 4:86935002-87240314
CIL_0000BS CIL_0000BS_0001 CGP 4:87160103-87322906

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0016567 IDA protein ubiquitination
GO:0031463 IDA Cul3-RING ubiquitin ligase complex
GO:0042787 IDA protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015344 klhl8 kelch-like 8 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000029312 Klhl8 kelch-like 8 protein_coding Mus_musculus

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