C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nitric oxide synthase 1, neuronal
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029361 Nos1 10090 + 5:117781032-117958840 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086451 Nos1-003 117842186-117954364 nonsense_mediated_decay
  ENSMUST00000102557 Nos1-002 117867114-117953909 protein_coding
  ENSMUST00000124194 Nos1-004 117781055-117867086 processed_transcript
  ENSMUST00000138554 Nos1-006 117919175-117925731 processed_transcript
  ENSMUST00000138579 Nos1-005 117781032-117867456 protein_coding
  ENSMUST00000142742 Nos1-001 117841850-117958840 protein_coding
  ENSMUST00000171055 Nos1-201 117867119-117953813 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000086451ENSMUST00000102557ENSMUST00000138579ENSMUST00000142742ENSMUST00000171055
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000086451 0.039±0.00 N/A N/A N/A N/A N/A N/A 0.007±0.00 N/A N/A 0.322±0.19 N/A 0.159±0.03
ENSMUST00000102557 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.346±0.00 0.501±0.00 N/A N/A
ENSMUST00000138579 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.454±0.83 N/A N/A
ENSMUST00000142742 0.045±0.02 0.054±0.01 2.248±0.99 0.424±0.00 1.330±0.39 0.053±0.02 0.082±0.03 0.005±0.00 0.069±0.00 8.976±1.01 0.278±0.04 0.381±0.25 0.128±0.04
ENSMUST00000171055 N/A N/A N/A N/A N/A 0.069±0.05 0.116±0.00 N/A N/A N/A 0.439±0.27 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0002028 IMP regulation of sodium ion transport
GO:0003958 IBA NADPH-hemoprotein reductase activity
GO:0004517 IEA nitric-oxide synthase activity
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005739 ISO mitochondrion
GO:0005829 IBA cytosol
GO:0005856 IDA cytoskeleton
GO:0006809 IEA nitric oxide biosynthetic process
GO:0006941 IMP striated muscle contraction
GO:0007263 IBA nitric oxide mediated signal transduction
GO:0009408 IEA response to heat
GO:0010181 IEA FMN binding
GO:0016529 IEA sarcoplasmic reticulum
GO:0018119 IDA peptidyl-cysteine S-nitrosylation
GO:0020037 IEA heme binding
GO:0031284 IBA positive regulation of guanylate cyclase activity
GO:0033555 IEA multicellular organismal response to stress
GO:0035066 IMP positive regulation of histone acetylation
GO:0042383 IDA sarcolemma
GO:0042738 IMP exogenous drug catabolic process
GO:0042995 IEA cell projection
GO:0043267 IMP negative regulation of potassium ion transport
GO:0045121 IDA membrane raft
GO:0045202 IDA synapse
GO:0045776 IBA negative regulation of blood pressure
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045909 IBA positive regulation of vasodilation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0051346 IMP negative regulation of hydrolase activity
GO:0051612 IDA negative regulation of serotonin uptake
GO:0051926 IMP negative regulation of calcium ion transport
GO:0055114 IEA:IBA oxidation-reduction process
GO:0071363 IMP cellular response to growth factor stimulus
GO:0098735 IMP positive regulation of the force of heart contraction
GO:1901206 IMP positive regulation of adrenergic receptor signaling pathway involved in heart process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068910 nos1 nitric oxide synthase 1 (neuronal) protein_coding Danio_rerio
ENSG00000089250 NOS1 nitric oxide synthase 1 (neuronal) protein_coding Homo_sapiens

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