C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nitric oxide synthase 1 (neuronal)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000068910 nos1 7955 - 5:13188827-13313998 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000099810 nos1-201 13193814-13313998 protein_coding
  ENSDART00000099822 nos1-001 13188827-13313998 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000099810ENSDART00000099822
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000099810 N/A 0.021±0.00 0.106±0.00 0.052±0.00 N/A
ENSDART00000099822 3.560±3.34 0.982±0.38 0.433±0.00 N/A 0.228±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001QM CIL_0001QM_0001 CGP 5:13188827-13501138

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003958 IBA NADPH-hemoprotein reductase activity
GO:0004517 IEA nitric-oxide synthase activity
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005516 IEA calmodulin binding
GO:0005622 IMP intracellular
GO:0005829 IBA cytosol
GO:0006809 IEA nitric oxide biosynthetic process
GO:0007263 IMP nitric oxide mediated signal transduction
GO:0010181 IEA FMN binding
GO:0016491 IEA oxidoreductase activity
GO:0020037 IEA heme binding
GO:0021517 IMP ventral spinal cord development
GO:0031284 IBA positive regulation of guanylate cyclase activity
GO:0045776 IBA negative regulation of blood pressure
GO:0045909 IBA positive regulation of vasodilation
GO:0046872 IEA metal ion binding
GO:0048668 IMP collateral sprouting
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0055114 IEA oxidation-reduction process
GO:0060218 IMP hematopoietic stem cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000089250 NOS1 nitric oxide synthase 1 (neuronal) protein_coding Homo_sapiens
ENSMUSG00000029361 Nos1 nitric oxide synthase 1, neuronal protein_coding Mus_musculus

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